Related Experiment Video
Updated: Jan 28, 2026

Treatment with Locking Intramedullary Nailing for Intertrochanteric Fracture of the Femur Utilizing a New Awl with a Distal Positioner
Published on: June 6, 2025
Dynamic Analysis of Perioperative Hidden Blood Loss in Intertrochanteric Fractures
Shuwei Tian1, Hui Li2, Meiyu Liu3
11 Hebei Provincial General Hospital, Shijiazhuang, Hebei, China.
Insights
Hidden blood loss in intertrochanteric fractures occurs before surgery and peaks by postoperative day 2. This study tracked hemoglobin changes and calculated blood loss in 79 patients undergoing surgery.
Area of Science:
- Orthopedic Surgery
- Trauma Care
- Hematology
Background:
- Intertrochanteric fractures are common injuries requiring surgical intervention.
- Perioperative blood loss, both visible and hidden, is a significant concern in these patients.
- Understanding the dynamics of hidden blood loss is crucial for optimizing patient management.
Purpose of the Study:
- To analyze the dynamic variation in perioperative hidden blood loss in patients with intertrochanteric fractures.
- To compare hemoglobin (Hb) changes and blood loss volumes between different perioperative blood transfusion groups.
Main Methods:
- Prospective analysis of 79 patients with intertrochanteric fractures treated with proximal femoral nail antirotation.
- Serial complete blood count assays performed preoperatively, on the day of surgery, and up to 7 days postoperatively.
- Calculation of total and hidden blood loss using the Gross equation; comparison of Hb levels and blood loss based on transfusion volumes.
Main Results:
- Lowest mean hemoglobin values occurred on postoperative day 2 (men) and day 3 (women).
- Average total blood loss ranged from 406.0 mL to 759.7 mL, with hidden blood loss comprising a significant portion.
- Hidden blood loss was observed to occur prior to surgery and resolve by postoperative day 2.
Conclusions:
- Perioperative hidden blood loss is a critical factor in patients with intertrochanteric fractures.
- Monitoring hemoglobin dynamics is essential for assessing blood loss and guiding transfusion strategies.
- Hidden blood loss begins before surgery and continues into the early postoperative period.
Abstract:
To analyze the dynamic variation in perioperative hidden blood loss in patients with intertrochanteric fracture. From January to December 2017, 79 patients with intertrochanteric fracture were treated with proximal femoral nail antirotation. Serial complete blood count assays were performed consecutively in the 3 days after admission, on the day of surgery, and 7 days postoperatively. Blood loss during surgery, postoperative drainage, and perioperative blood transfusion volumes were recorded. Dynamic changes in hemoglobin (Hb) prior to surgery were recorded and compared between males and females. Patients were divided into the no blood transfusion group, the 400-mL blood transfusion group, and the 800-mL blood transfusion group depending on the volume of perioperative blood transfusion. Total and hidden blood loss were separately calculated according to the Gross equation. Lowest mean Hb values occurred on day 2 after admission among men (104.8 g/L) and on day 3 after admission among women (98.6 g/L). The average Hb decrease was 11.4 g/L, 11.8 g/L, and 8.9 g/L in the no, 400-mL, and 800-mL blood transfusion groups, respectively. The lowest Hb value occurred on postoperative day 2. Hemoglobin increased on postoperative day 3 and stabilized by day 6. In the no blood transfusion group, the average total blood loss was 406.0 ± 255.6 mL, 628.3 ± 267.2 mL, and 759.7 ± 322.1 mL in the no blood transfusion, 400-mL blood transfusion, and 800-mL blood transfusion groups, respectively, and hidden blood loss was 326.0 ± 246.6 mL, 512.1 ± 247.3 mL, and 596.1 ± 306.9 mL, respectively. Perioperative hidden blood loss occurred prior to surgery for intertrochanteric fracture and ended on postoperative day 2.
Related Concept Videos
Line Loss
Line loss impacts power delivery efficiency in a balanced three-phase circuit. The symmetry in such a circuit simplifies the...
Reducing Line Loss
With a step-up transformer at the source, the voltage is increased, thereby reducing the current in the transmission lines since power loss in...
Fractures: Bone Repair
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
Energy Losses in Transformers
There are four main reasons for energy losses in transformers.
The first cause can be the high resistance of the...
Major Losses in Pipes
Fluid flow can be classified as laminar or turbulent, primarily based on the Reynolds number. This dimensionless number reflects the relative influence of inertial to viscous...
Minor Losses in Pipes
Valves play a significant role in generating minor losses by obstructing or redirecting the fluid flow. When a valve is closed or partially closed, it restricts the flow...

