Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

3.3K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
3.3K
Local Anesthetics: Clinical Application as Spinal Anesthesia01:11

Local Anesthetics: Clinical Application as Spinal Anesthesia

1.4K
Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
1.4K
Local Anesthetics: Clinical Application as Epidural Anesthesia01:29

Local Anesthetics: Clinical Application as Epidural Anesthesia

718
Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
718
Trial and Error and Algorithm01:12

Trial and Error and Algorithm

403
A problem-solving strategy is a plan of action used to find a solution. Different strategies have distinct action plans. Trial and error involves trying different solutions until one works. For instance, to fix a broken printer, you might check ink levels, ensure the paper tray isn't jammed, and verify the printer's connection to your laptop. This method can be time-consuming but is commonly used. Thomas Edison, for example, used trial and error to find a suitable filament for the light...
403
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia01:16

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

1.3K
Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
1.3K
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation01:30

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation

768
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
768

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quality of life results of addition of androgen deprivation therapy and pelvic lymph node treatment to prostate bed salvage radiotherapy: NRG Oncology/RTOG 0534 SPPORT.

International journal of radiation oncology, biology, physics·2026
Same author

The Impact of an Outpatient Urgent Care Clinic on Patients Treated for Head and Neck Cancer.

Clinical journal of oncology nursing·2026
Same author

Concurrent Versus Sequential Radiation Dose Escalation to the Surgical Cavity for Conservative Treatment of High-Risk Early Breast Cancer: NRG/RTOG 1005 Phase III Trial.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2026
Same author

Integrating natural language processing into radiation oncology: a practical guide to transformer architecture and large language models.

BJR artificial intelligence·2026
Same author

AKT, ATR, and Notch Inhibitors Radiosensitize a Preclinical Model of Adenoid Cystic Carcinoma.

Head & neck·2026
Same author

Quality of Life in Patients With p16+ Oropharyngeal Cancer Receiving Accelerated Radiation Therapy With Either Cisplatin or Cetuximab in the NRG/RTOG 1016 Randomized Controlled Trial.

International journal of radiation oncology, biology, physics·2026

Related Experiment Video

Updated: Jan 28, 2026

Area-based Image Analysis Algorithm for Quantification of Macrophage-fibroblast Cocultures
07:05

Area-based Image Analysis Algorithm for Quantification of Macrophage-fibroblast Cocultures

Published on: February 15, 2022

2.9K

Evaluation and Clinical Application of a Commercially Available Iterative Reconstruction Algorithm for CBCT-Based

Weihua Mao1, Chang Liu1, Stephen J Gardner1

  • 11 Department of Radiation Oncology, Henry Ford Health System, Detroit, MI, USA.

Technology in Cancer Research & Treatment
|February 27, 2019
PubMed
Summary

A new iterative cone-beam computed tomography (CBCT) reconstruction algorithm significantly reduces image noise and artifacts compared to standard filtered back-projection methods. This enhancement improves image quality for CBCT-based image-guided applications.

Keywords:
CBCTiterative reconstructionlow contrast detectionnoise reductionscatter correction

More Related Videos

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible
10:42

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible

Published on: January 28, 2020

6.9K
Evaluation of Commercial-Off-The-Shelf Wrist Wearables to Estimate Stress on Students
12:51

Evaluation of Commercial-Off-The-Shelf Wrist Wearables to Estimate Stress on Students

Published on: June 16, 2018

7.9K

Related Experiment Videos

Last Updated: Jan 28, 2026

Area-based Image Analysis Algorithm for Quantification of Macrophage-fibroblast Cocultures
07:05

Area-based Image Analysis Algorithm for Quantification of Macrophage-fibroblast Cocultures

Published on: February 15, 2022

2.9K
A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible
10:42

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible

Published on: January 28, 2020

6.9K
Evaluation of Commercial-Off-The-Shelf Wrist Wearables to Estimate Stress on Students
12:51

Evaluation of Commercial-Off-The-Shelf Wrist Wearables to Estimate Stress on Students

Published on: June 16, 2018

7.9K

Area of Science:

  • Medical Imaging
  • Radiology
  • Image Reconstruction

Background:

  • Cone-beam computed tomography (CBCT) is crucial for image-guided interventions.
  • Standard filtered back-projection (FBP) reconstruction in CBCT can be limited by noise and artifacts.
  • Iterative reconstruction algorithms offer potential for improved image quality.

Purpose of the Study:

  • To quantitatively evaluate the image quality of a new iterative CBCT reconstruction algorithm.
  • To compare the performance of the iterative algorithm against standard FBP reconstruction.
  • To assess the impact of the iterative algorithm on noise, resolution, and artifacts.

Main Methods:

  • A new iterative CBCT reconstruction pipeline incorporating scatter correction and statistical reconstruction was developed.
  • Image quality was assessed using phantoms (QA and anthropomorphic head) and clinical patient data (head/neck and prostate).
  • Metrics included uniformity, HU constancy, spatial resolution, low contrast detection, noise level, and contrast-to-noise ratio.

Main Results:

  • The iterative CBCT algorithm significantly reduced noise across all tested protocols (Head and Pelvis scans).
  • Noise reduction ranged from 28.8 HU to as low as 5.9 HU in phantom studies.
  • Artifacts were reduced, and noise in patient data decreased by 62% ± 15%.

Conclusions:

  • The iterative CBCT reconstruction algorithm demonstrates superior performance in reducing noise and artifacts compared to FBP.
  • Significant improvements in noise and contrast-to-noise ratio were observed.
  • These enhancements are expected to improve the accuracy of CBCT-guided applications.