Related Experiment Video
Updated: Jan 28, 2026

PLGA Nanoparticles Formed by Single- or Double-emulsion with Vitamin E-TPGS
Published on: December 27, 2013
Vitamin D supplementation: are multivitamins sufficient?
Rebecca J Moon1,2, Elizabeth M Curtis1, Cyrus Cooper1,3,4
1MRC Lifecourse Epidemiology Unit, University Hospital Southampton, Southampton, UK.
Many children's multivitamins do not contain the recommended 400 IU/day of vitamin D. Parents should check labels carefully to ensure adequate vitamin D intake for children's bone health.
Area of Science:
- Pediatric Nutrition
- Public Health
- Dietary Supplements
Background:
- Public Health England recommends 400 IU/day of vitamin D for children over one year old.
- Vitamin D is crucial for bone health and development in children.
Purpose of the Study:
- To assess the vitamin D content of commercially available children's multivitamins and vitamin D supplements in the UK.
- To determine the proportion of products meeting the recommended daily intake of 400 IU/day.
Main Methods:
- A survey of multivitamins and vitamin D supplements marketed to children under 12 years.
- Products were sourced from nine UK supermarkets and health supplement retailers.
- Vitamin D content was verified using manufacturer websites and product packaging.
Main Results:
- 67 different multivitamin products were analyzed, with vitamin D content ranging from 0 to 800 IU/day.
- Only 25%-36% of multivitamins provided the recommended 400 IU/day, varying by child's age.
- Supplements specifically for 'healthy bones' or containing only vitamin D were more likely to meet the 400 IU/day recommendation (57%-67%).
Conclusions:
- A significant number of children's multivitamin products do not supply the recommended 400 IU/day of vitamin D.
- Healthcare professionals should be aware of this discrepancy when advising on vitamin D supplementation.
- Parents and caregivers are advised to select products that explicitly provide at least 400 IU/day of vitamin D for their children.
More Related Videos
Related Concept Videos
Vitamins
Role of Skin in Vitamin D Synthesis
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
Mineral, Vitamin and Water Absorption
Role of Vitamins in Maintaining Bone Health
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
Cofactors and Coenzymes

