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Minimal change disease and Kimura's disease responding to tacrolimus therapy
Manish R Balwani1, Charulata P Bawankule2, Amit Pasari1
1Department of Nephrology, Jawaharlal Nehru Medical College, Wardha, Maharashtra, India.
Abstract:
Kimura's disease (KD) usually presents with a subcutaneous swelling and associated lymphadenopathy in the periauricular area. KD has a tendency to involve the kidneys. Proteinuria is reported in 12%-16% of cases, and around 60%-70% of them develop nephrotic range proteinuria. We are reporting a case of KD which developed around 12 years later in a patient of biopsy-proven steroid responsive minimal change disease. Recurrent swellings of KD and subnephrotic range proteinuria responded to low-dose tacrolimus therapy (0.05 mg/kg).