Exploring the Control in Antibacterial Activity of Silver Triangular Nanoplates by Surface Coating Modulation
Jamila Djafari1,2,3, Carlos Fernández-Lodeiro1,2, Adrián Fernández-Lodeiro1,2,3
1BIOSCOPE Group, LAQV@REQUIMTE, Chemistry Department, Faculty of Science and Technology, NOVA University Lisbon, Caparica, Portugal.
Frontiers in Chemistry
|February 27, 2019
Summary
Silver triangular nanoplates (AgNTs) with organic coatings show enhanced antibacterial properties compared to spherical silver. Silica coatings reduce but do not eliminate antimicrobial effects, with surface charge being crucial for certain bacteria.
Area of Science:
- Nanotechnology
- Materials Science
- Microbiology
Background:
- Silver triangular nanoplates (AgNTs) are synthesized and characterized.
- Surface modification of nanomaterials can tune their biological activity.
- Understanding coating effects on AgNTs' antibacterial properties is crucial.
Purpose of the Study:
- To synthesize and characterize AgNTs and their silica-coated composites.
- To investigate the influence of organic (PVP, MHA) and inorganic (silica) coatings on AgNTs' antibacterial efficacy.
- To evaluate the role of surface charge in the antimicrobial activity of AgNTs@Si.
Main Methods:
- Synthesis and characterization of AgNTs and AgNT-silica nanocomposites.
- Application of organic coatings (PVP, MHA) and inorganic silica coatings (≈5 nm).
- Testing antibacterial properties against Gram-positive and Gram-negative bacteria.
Main Results:
- Organic coatings (MHA) on AgNTs enhanced antimicrobial properties compared to spherical silver colloids.
- Thick inorganic silica coatings reduced but did not abolish the antibacterial effect of AgNTs.
- Surface charge of AgNTs@Si significantly influenced activity against *S. aureus*.
Conclusions:
- Surface engineering of AgNTs, particularly with organic coatings, can modulate and enhance antibacterial effects.
- Silica coating offers a degree of antimicrobial activity, influenced by surface properties.
- AgNTs show promise as antimicrobial agents, with coating strategies allowing for tailored applications.
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