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Related Concept Videos

Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

923
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
923
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
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Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

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Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
586
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

1.0K
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
1.0K
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

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Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
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Imaging Mycobacterium tuberculosis in Mice with Reporter Enzyme Fluorescence
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The many faces of tuberculosis.

Anirban Mandal1, Amitabh Singh2

  • 1Department of Pediatrics, Sitaram Bhartia Institute of Science and Research, New Delhi, India.

International Journal of Pediatrics & Adolescent Medicine
|February 27, 2019
PubMed
Summary

Tuberculosis (TB) rare multifocal bone lesions and orbital mass in a child were diagnosed using Xpert MTB/RIF. Prompt antitubercular treatment led to recovery, highlighting the need for awareness of atypical TB presentations.

Keywords:
Intraorbital abscessJungling's diseasePediatric

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Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Radiology

Background:

  • Tuberculosis (TB) can manifest with rare multifocal cystic bone lesions, known as Jungling's disease.
  • Intra-orbital and calvarial involvement in pediatric TB is exceptionally uncommon, particularly in immunocompetent individuals.

Observation:

  • A 3-year-old immunocompetent boy presented with acute, painless right intra-orbital swelling.
  • He also had multifocal bony lesions on the right tibia and frontal bone.

Findings:

  • The Xpert MTB/RIF assay on aspirated orbital pus confirmed tubercular etiology.
  • The patient demonstrated significant clinical improvement following initiation of antitubercular therapy.

Implications:

  • Atypical presentations of TB in children, including multifocal osteolytic lesions and orbital abscesses, require consideration.
  • Timely diagnosis utilizing advanced methods like Xpert MTB/RIF and prompt treatment are crucial for favorable outcomes in pediatric TB.