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Hepatitis C in Hemodialysis Units: diagnosis and therapeutic approach

Natasha Silva Constancio1,2, Maria Lucia Gomes Ferraz3,4, Carmen Tzanno Branco Martins2

  • 1Associação Renal Vida Rio do Sul, Rio do Sul, SC, Brasil.

Jornal Brasileiro De Nefrologia
|February 27, 2019
PubMed

Insights

Hepatitis C virus (HCV) is three times more prevalent in Brazilian dialysis units than the general population. New antiviral treatments offer a feasible path to cure and eradicate HCV in these vulnerable patients.

Area of Science:

  • Nephrology
  • Hepatology
  • Infectious Diseases

Background:

  • The prevalence of Hepatitis C Virus (HCV) in Brazilian hemodialysis units (HU) is 3.3%, significantly higher than the general population.
  • HCV poses a risk of horizontal transmission within HU, necessitating rapid diagnostic approaches.
  • Recent advancements in antiviral therapies offer promising prospects for HCV cure and eradication.

Purpose of the Study:

  • To present a proposed approach for managing HCV within hemodialysis units.
  • To address the high prevalence and transmission risks of HCV in Brazilian HU.
  • To leverage new antiviral treatments for HCV eradication in patients with chronic kidney disease.

Main Methods:

  • This review article synthesizes current data and expert recommendations.
  • It outlines strategies for HCV diagnosis and management in the HU setting.
  • The proposal considers the latest developments in antiviral drug therapy.

Main Results:

  • The review highlights the elevated HCV burden in Brazilian HU.
  • It emphasizes the feasibility of achieving HCV cure and eradication with modern treatments.
  • The proposed approach aims to mitigate transmission and improve patient outcomes.

Conclusions:

  • A proactive and integrated strategy is crucial for controlling HCV in HU.
  • Effective management of HCV in dialysis patients is achievable with current therapeutic options.
  • Collaboration between nephrology and hepatology societies is key to tackling HCV in this population.

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