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Treatments of sleep bruxism in children: A systematic review and meta-analysis

Gaetano Ierardo1, Marta Mazur1, Valeria Luzzi1

  • 1Department of Oral and Maxillofacial Sciences, Sapienza University of Rome , Rome, Italy.

Cranio : the Journal of Craniomandibular Practice
|February 27, 2019
PubMed

Insights

Treatment for childhood sleep bruxism (SB) is not well-established. Hydroxyzine therapy showed the strongest efficacy in a systematic review, but more research is needed.

Area of Science:

  • Pediatric Dentistry
  • Sleep Medicine
  • Pharmacology

Background:

  • Sleep bruxism (SB) in children lacks established treatment guidelines.
  • Evidence-based recommendations for pediatric SB therapy are needed for children aged 2-17.

Purpose of the Study:

  • To develop evidence-based recommendations for sleep bruxism therapy in children.
  • To synthesize current evidence on the efficacy of different SB treatments in pediatric populations.

Main Methods:

  • Systematic review and meta-analysis of literature.
  • Searches conducted in MedLine (PubMed), Web of Science, Scopus, and Cochrane Library up to November 30, 2017.
  • Inclusion of 10 papers for qualitative synthesis and 3 for meta-analysis (total 94 patients).

Main Results:

  • Hydroxyzine therapy demonstrated the highest efficacy for treating sleep bruxism in children (OR 10.63; 95% CI, 1.48 to 76.08).
  • Flurazepam and Melissa officinalis showed a weaker association with reduced SB symptoms.
  • Limited data available, with a small sample size in the meta-analysis.

Conclusions:

  • Current data on pediatric sleep bruxism treatments are scarce.
  • High-quality studies with larger patient cohorts and standardized diagnostic criteria are essential for future research.
  • Further investigation is required to establish definitive treatment protocols for childhood sleep bruxism.

Keywords:
Sleep bruxismchildrenelectromyography (EMG)meta-analysissystematic reviewtreatment

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