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Sample transportation - an overview.

Mads Nybo1, Janne Cadamuro2, Michael P Cornes3

  • 1Department of Clinical Biochemistry and Pharmacology, Odense University Hospital, Sdr. Boulevard 29, Odense 5000, Denmark.

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Summary
This summary is machine-generated.

Sample transportation is a critical, complex step in the preanalytical phase, impacting lab results. This review details options and essential preanalytical considerations for quality control and regulatory compliance.

Keywords:
preanalyticalsample transportation

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Area of Science:

  • Clinical Laboratory Science
  • Preanalytical Workflow Optimization
  • Medical Logistics

Background:

  • Sample transportation is a vital yet often overlooked component of the preanalytical pathway.
  • Inefficiencies in sample transport can significantly delay laboratory results for clinicians.
  • The complexity of sample logistics necessitates careful planning and resource allocation.

Purpose of the Study:

  • To review available options for blood sample transportation.
  • To highlight critical preanalytical factors influencing sample integrity during transit.
  • To emphasize the importance of quality control and regulatory adherence in sample logistics.

Main Methods:

  • Literature review of sample transportation methods and associated challenges.
  • Analysis of preanalytical variables impacting sample quality during transport.
  • Examination of relevant ISO standards (15189, 20658) and regulatory requirements (e.g., GDPR).

Main Results:

  • Identified key considerations including performance specifications, automated system quality control, and sample integrity monitoring.
  • Highlighted the necessity of continuous temperature surveillance, especially for external samplers.
  • Emphasized the need for laboratories to adapt to changing clinical demands and new regulations.

Conclusions:

  • Effective sample transportation requires robust planning, dedicated resources, and stringent quality control measures.
  • Laboratories must ensure sample integrity and compliance with evolving standards and regulations.
  • Proactive management of the preanalytical transportation phase is crucial for timely and accurate laboratory diagnostics.