Polymeric nanodroplets: an emerging trend in gaseous delivery system

Area of Science:

• Nanotechnology
• Materials Science
• Biomedical Engineering

Background:

• Nanotechnology products are increasingly important for drug delivery and diagnostics.
• Nanodroplets (NDs) are emerging as versatile carriers for gases and active substances.
• NDs offer potential in theranostics, drug delivery, and diagnostic devices.

Purpose of the Study:

• To provide a comprehensive review of nanodroplets (NDs).
• To discuss the properties, preparation, characterization, and applications of NDs.
• To highlight the potential of NDs in advanced healthcare applications.

Main Methods:

• Review of existing literature on nanodroplets.
• Analysis of nanodroplet properties, polymers, and mathematical theories.
• Examination of characterization techniques, animal models, and toxicity studies.

Main Results:

• Nanodroplets are multifunctional carriers with a polymer-drug shell and gas/liquid core.
• Advantages include cost-effectiveness, compatibility with diverse core molecules, large surface area, and target specificity.
• NDs show promise in treating conditions like hypoxia, multiple sclerosis, and cancer.

Conclusions:

• Nanodroplets represent a significant advancement in nanocarrier technology.
• Their unique properties facilitate broad applications in healthcare and theranostics.
• Future developments are expected in personalized medicine and precise theranostics.