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Updated: Jan 20, 2026

Microscopic Cyst Resection for the Treatment of Patients Diagnosed with Epididymal Cyst
Published on: March 31, 2023
Aneurysmal bone cyst treated with percutaneous doxycycline: is a single treatment sufficient?
Jason T K Woon1,2, Damien Hoon3, Andrew Graydon4
1Anatomy and Medical Imaging, University of Auckland, Park Road, Grafton, Auckland, 1023, New Zealand.
Objective:
The purpose of this case series is to report on the effectiveness of a single percutaneous injection of doxycycline as a primary treatment for aneurysmal bone cyst (ABC).
Materials And Methods:
A retrospective cohort study was conducted on seven patients diagnosed with ABC at various anatomical sites, with the intention to treat by a single percutaneous injection of doxycycline. Mean patient age was 14 years.
Results:
Signs of treatment response were seen in six of seven patients after one injection. Three of the seven received a second treatment, despite signs of response. Another had expansion of the lesion after treatment, requiring excision. In total, three patients had a single injection of doxycycline as their sole treatment and another three showed signs of response after a single injection.
Conclusions:
A single percutaneous injection of doxycycline should be considered a viable primary treatment option for ABC.
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