Related Experiment Video
Updated: Jan 28, 2026

Production and Targeting of Monovalent Quantum Dots
Published on: October 23, 2014
Photostability of quantum dot micelles under ultraviolet irradiation
Shanmugavel Chinnathambi1, Nobutaka Hanagata1,2
1International Center for Young Scientists, National Institute for Materials Science, Tsukuba, Ibaraki, Japan.
Abstract:
Phospholipid quantum dot micelles are useful for bio-applications because of their amphiphilicity and exceptional biocompatibilities. We investigated the uptake of phospholipid [polyethylene glycol (PEG), biotin, and folic acid terminated] modified CdSe/ZnS quantum dot micelles by cancer cells and its photostability under ultrviolet light in the C spectrum (UV-C) (254 nm) or UV-A (365 nm) light irradiation. The stability of micelles to the exposure of UV-C and UV-A light was assessed. Biotin-modified quantum dot micelles give photoluminescence enhancement under UV-C light irradiation. Folate modified micelle under UV-C and UV-A results show considerable photoluminescence enhancement. Photoluminescence lifetime measurements showed 7.04, 8.11 and 11.42 ns for PEG, folate, and biotin terminated phospholipid micelles, respectively. Folate and biotin-modified quantum dot micelles showed excellent uptake by HeLa cells under fluorescence confocal microscopy. Phospholipid CdSe/ZnS quantum dot micelles can be potentially used for diagnosis and treatment of cancer in the future.
Related Concept Videos
Quantum Numbers
The Quantum-Mechanical Model of an Atom
The Dot Product
Dot Product
In engineering, the dot product of any two vectors is the product of the magnitudes of the vectors and the cosine of the angle between them. It is denoted by a dot symbol between the two vectors.
Consider a vehicle pulling an object along the ground using a rope. If the rope makes an angle with the horizontal axis, the work done can be calculated using the dot product of the force applied and the object's displacement.
The dot...
Ultraviolet and Visible (UV–Vis) Spectroscopy: Overview
Dot Product: Problem Solving
Identify the problem: Start by reading the problem and...

