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Throughout its ~4.5 billion year history, the Earth has experienced periods of warming and cooling. However, the current drastic increase in global temperatures is well outside of the Earth’s cyclic norms, and evidence for human-caused global climate change is compelling. Paleoclimatology, the study of ancient climate conditions, provides ample evidence for human-caused global climate change by comparing recent conditions with those in the past.
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Updated: Jan 28, 2026

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
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Global rosacea treatment guidelines and expert consensus points: The differences.

Juliandri Juliandri1, Xiaoyan Wang1, Zijing Liu1

  • 1Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Journal of Cosmetic Dermatology
|February 28, 2019
PubMed
Summary
This summary is machine-generated.

This review compares current rosacea treatments across four guidelines. Future research should focus on large-scale trials for new therapies, guiding evidence-based rosacea management.

Keywords:
erythemaphymatousrosaceatelangiectasiatreatment

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Area of Science:

  • Dermatology
  • Clinical Research

Background:

  • Rosacea is a common, chronic inflammatory skin condition.
  • Treatment presents a challenge for dermatologists, involving skincare, medications, and lasers.
  • Therapeutic choices depend on rosacea subtype and patient symptoms.

Purpose of the Study:

  • To review and compare current rosacea treatment strategies.
  • Analysis included therapies for all rosacea severities.
  • Comparison was based on four distinct clinical guidelines.

Main Methods:

  • Systematic literature search using PubMed with specific keywords.
  • Included study types: randomized controlled trials, observational studies, controlled clinical trials, and clinical trials.
  • Hand-searching identified additional relevant publications and guidelines.

Main Results:

  • Initial search yielded 421 records; 25 studies met inclusion criteria.
  • Five additional manuscripts and four guidelines were included.
  • The review synthesized findings from selected high-quality evidence.

Conclusions:

  • Guideline-based diagnosis and treatment are crucial for scientific criteria in rosacea management.
  • Large-scale randomized controlled trials are needed for novel treatments and drug formulations.
  • Current rosacea treatments generally target Demodex mites, inflammation, and angiogenesis.