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Early and Medium Outcomes of On-Pump Beating-Heart versus Off-Pump CABG in Patients with Moderate Left Ventricular
Weitie Wang1, Yong Wang1, Hulin Piao1
1Department of Cardiovascular Surgery, 2nd Hospital of Bethune, Jilin University, Changchun, Jilin, China.
Insights
On-pump beating-heart coronary artery bypass grafting (CABG) offers better outcomes for patients with moderate left ventricular dysfunction. This surgical technique showed improved graft numbers and ejection fraction compared to off-pump CABG, with comparable early safety.
Area of Science:
- Cardiovascular Surgery
- Cardiac Surgery Outcomes
- Myocardial Revascularization
Background:
- Patients with moderate left ventricular dysfunction (LVEF 30-40%) present unique challenges for surgical revascularization.
- Comparing on-pump beating-heart (OPBH) and off-pump coronary artery bypass grafting (OPCABG) is crucial for optimizing patient care.
Purpose of the Study:
- To compare the early and medium-term clinical outcomes of OPBH versus OPCABG in patients with LVEF between 30% and 40%.
Main Methods:
- Retrospective analysis of ischemic heart disease patients (LVEF 30-40%) undergoing surgical revascularization between January 2013 and December 2017.
- Patients were divided into OPBH (n=44) and OPCABG (n=68) groups.
- Clinical data and early/medium outcomes were investigated and compared.
Main Results:
- Both groups had similar baseline characteristics and in-hospital mortality.
- OPBH patients received more grafts and showed significantly improved LVEF compared to OPCABG.
- OPBH group had increased drainage in the first 12 hours, but no significant differences in reoperation for bleeding or ventilation duration.
- OPBH patients demonstrated significantly lower major adverse cardiovascular events (MACE)-free survival time during medium-term follow-up.
Conclusions:
- On-pump beating-heart CABG is a safe and acceptable alternative for patients with moderate left ventricular dysfunction.
- OPBH provided better mid-term MACE-free survival compared to OPCABG in this patient cohort.
Objective:
This study aims to compare the early and medium outcomes of on-pump beating-heart (OPBH) coronary artery bypass grafting (CABG) and off-pump CABG (OPCABG) in patients with left ventricular ejection fraction (LVEF) between 30% and 40%.
Methods:
This is a retrospective study of ischemic heart disease patients with LVEF between 30% and 40% who underwent surgical revascularization from January 2013 to December 2017. Patients were divided into OPBH group (n=44) and OPCABG group (n=68), according to the surgical method. Clinical material with early and medium outcomes were investigated and compared between these groups.
Results:
The two groups had similar baseline. Two OPBH patients and 3 OPCABG patients died in the hospital, which had no statistical significance (P>0.05). OPBH patients received a greater number of grafts (3.74±0.84) and presented more improved LVEF (45.92±7.11%) than OPCABG patients (3.36±0.80) and (42.81±9.29%), respectively, which had statistical significance (P<0.05). An increased amount of drainage during the first 12 hours was found in the OPBH group (P<0.05). Reoperation for bleeding, duration of mechanic ventilation, and other early outcomes had no statistical significance between the two groups. During the medium-time follow-up, OPBH patients showed significantly lower major adverse cardiovascular events (MACE)-free survival time (P=0.049) than OPCABG patients.
Conclusion:
The OPBH technique was a safe and an acceptable alternative for surgical revascularization in patients with moderate left ventricular dysfunction which provided better mid-term MACE-free survival compared with OPCABG.
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