The identification and treatment of intestinal malrotation in older children

Charlene Dekonenko1, Joseph A Sujka1, Katrina Weaver1

  • 1Department of Surgery, Children's Mercy Kansas City, 2401 Gillham Road, Kansas City, MO, 64108, USA.

Insights

Intestinal malrotation can occur in patients over one year old, often presenting with vomiting or abdominal pain. Upper GI (UGI) series are effective for diagnosing this condition, leading to symptom alleviation after surgical intervention.

Area of Science:

  • Pediatric Surgery
  • Gastroenterology
  • Radiology

Background:

  • Intestinal malrotation is typically diagnosed in infants.
  • The incidence and presentation of malrotation in older children and adults are less understood.
  • Atypical or asymptomatic presentations can delay diagnosis.

Purpose of the Study:

  • To determine the incidence of intestinal malrotation in patients over one year of age.
  • To characterize the clinical presentation, diagnostic imaging, and intra-operative findings in this age group.
  • To evaluate the effectiveness of surgical intervention for alleviating symptoms.

Main Methods:

  • Retrospective review of patients over one year old diagnosed with malrotation between 2000 and 2015.
  • Analysis of demographics, clinical presentation, imaging studies, and surgical outcomes.
  • Exclusion of patients with predisposing conditions for malrotation.

Main Results:

  • 77 out of 246 (31%) patients diagnosed with malrotation were over one year old.
  • Vomiting (68%) and abdominal pain (57%) were the most common symptoms.
  • Upper GI (UGI) series diagnosed malrotation in 88% of cases, confirmed surgically in 73 of 75 patients.
  • Intra-operative findings included malrotated (60%) or non-rotated (33%) intestinal orientation, with obstruction in 22% and volvulus in 12%.
  • 58% of patients experienced symptom alleviation post-surgery.

Conclusions:

  • Intestinal malrotation should be considered in the differential diagnosis for patients over one year old, regardless of age.
  • Variable clinical presentations necessitate a high index of suspicion.
  • UGI series are crucial for prompt diagnosis and timely surgical intervention, leading to symptom resolution.
Abstract

Related Concept Videos

Anatomy of the Intestines01:23

Anatomy of the Intestines

Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
87.3K
Small Intestine01:15

Small Intestine

The small intestine is primarily responsible for digestion and nutrient absorption. It spans from the pyloric sphincter to the ileocecal valve and connects to the large intestine.
The small intestine is divided into three main sections - the duodenum, jejunum, and ileum. The duodenum, approximately 25 cm long, is nearest the stomach. It acts as a 'mixing bowl,' where chyme (partially digested food) blends with digestive enzymes from the pancreas and liver. The duodenum's unique...
3.8K
Large Intestine01:09

Large Intestine

The large intestine is divided into three main regions: the cecum, colon, and rectum. Extending from the ileocecal valve to the anus, it frames the small intestine on three sides.
The ileocecal sphincter, a mucous membrane fold, guards the opening from the ileum to the large intestine. This valve permits material from the small intestine to pass into the large intestine. Attached to the ileocecal valve is the cecum. This small pouch, approximately 6 cm long, has a twisted, coiled tube known as...
4.9K
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
283
Histology of the Large Intestine01:26

Histology of the Large Intestine

The large intestine, a vital component of the gastrointestinal tract, is structured with four main layers: the mucosa, submucosa, muscularis, and serosa. Each layer performs a distinct role in facilitating the smooth functioning of the large intestine.
The innermost mucosa layer comprises simple columnar epithelium, lamina propria, and muscularis mucosae. This layer is primarily populated with absorptive cells, tasked with water absorption, and goblet cells, responsible for secreting mucus to...
3.0K
Histology of the Small Intestine01:27

Histology of the Small Intestine

The small intestine exhibits a unique histological structure that significantly enhances its function in digestion and nutrient absorption. These structures include circular folds, villi, and various specialized cells that collectively facilitate the digestion of food.
The intestinal lining features transverse folds called circular folds, each housing fingerlike projections known as intestinal villi. These villi are covered by a layer of simple columnar epithelium, also referred to as...
3.7K