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Vitamins01:30

Vitamins

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Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
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Role of Skin in Vitamin D Synthesis01:23

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The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
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Mineral, Vitamin and Water Absorption01:27

Mineral, Vitamin and Water Absorption

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Electrolytes are essential minerals and ions primarily obtained from the diet and absorbed through the gastrointestinal tract. Most electrolytes are absorbed in the small intestine. While the absorption of iron and calcium primarily occurs in the duodenum, calcium is also absorbed in the jejunum and ileum. In these regions, passive diffusion contributes to its absorption alongside active transport mechanisms in the duodenum. These ions can exit the enterocytes through specialized active...
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Role of Vitamins in Maintaining Bone Health01:25

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The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
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Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants01:18

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Oral anticoagulants are vital tools in preventing and treating blood clotting disorders. This diverse class of medications can be categorized as vitamin K antagonists, exemplified by warfarin, and direct thrombin inhibitors (DTIs), such as dabigatran, as well as factor Xa inhibitors, including rivaroxaban.
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Overview of Metabolism01:40

Overview of Metabolism

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Living cells constantly carry out various chemical reactions which are necessary for their proper functioning. These reactions are interlinked to one another via multiple pathways. The collection of these chemical reactions is known as metabolism.
Plant Metabolism
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PLGA Nanoparticles Formed by Single- or Double-emulsion with Vitamin E-TPGS
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Overview on vitamin D and sunbed use.

L Pierret1, M Suppa2, S Gandini3

  • 1Department of Dermatology, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel (VUB), Brussels, Belgium.

Journal of the European Academy of Dermatology and Venereology : JEADV
|February 28, 2019
PubMed
Summary

Sunbeds can temporarily boost vitamin D levels but pose significant cancer risks. Vitamin D supplementation is a safer alternative for addressing vitamin D deficiency.

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Area of Science:

  • Dermatology
  • Endocrinology
  • Public Health

Background:

  • Vitamin D plays a crucial role in preventing various diseases, including cardiovascular, autoimmune, and oncologic conditions.
  • Cutaneous synthesis of vitamin D is primarily dependent on ultraviolet (UV) B light exposure.
  • Sunbeds artificially increase serum vitamin D levels, but these effects are often transient.

Purpose of the Study:

  • To evaluate the risk-benefit ratio of sunbed use for vitamin D status.
  • To address the artificial tanning industry's promotion of sunbeds as a safe therapeutic measure.
  • To inform the public about the carcinogenic risks associated with UV radiation from sunbeds.

Main Methods:

  • Review of scientific literature on vitamin D synthesis, sunbed use, and cancer risk.
  • Analysis of data regarding the efficacy and duration of vitamin D increase from sunbed exposure.
  • Assessment of the World Health Organization's classification of UV-emitting devices.

Main Results:

  • Sunbed use leads to a transient increase in serum vitamin D levels.
  • The World Health Organization classifies UV-emitting tanning devices as group-1 carcinogens.
  • Sunbed use significantly elevates the risk of developing melanoma and non-melanoma skin cancer.

Conclusions:

  • The carcinogenic risks of sunbed use outweigh the transient benefits of increased vitamin D levels.
  • Vitamin D supplementation is a safer and more effective strategy for managing vitamin D deficiency or insufficiency.
  • Artificial tanning devices should not be considered a viable option for achieving adequate vitamin D status due to their significant health risks.