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Published on: March 1, 2022
Effect of patent ductus arteriosus on pulmonary vascular disease
Ranjit Philip1, Jason Nathaniel Johnson1,2, Ronak Naik1
1Division of Pediatric Cardiology, University of Tennessee Health Science Center, Le Bonheur Children's Hospital, Memphis, Tennessee.
Insights
A patent ductus arteriosus (PDA) can cause serious heart and lung issues in premature infants. This review examines PDA
Area of Science:
- Neonatal cardiology
- Pediatric cardiovascular research
Background:
- Hemodynamic effects of patent ductus arteriosus (PDA) include systemic hypoperfusion and left ventricular volume overload.
- A hemodynamically significant PDA can lead to long-standing pulmonary vascular changes.
Abstract:
The hemodynamic effects of a patent ductus arteriosus (PDA) are well known including systemic hypoperfusion and volume overload on the left ventricle. This article aims to provide a review of the long-standing effect of a hemodynamically significant PDA on the pulmonary vasculature and the role of cardiac catheterization in preterm infants with a PDA and pulmonary hypertension.
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