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Overview of transcatheter patent ductus arteriosus closure in preterm infants

Myriam Almeida-Jones1,2, Nai Yu Tang1,2, Aneela Reddy3

  • 1Guerin Family Congenital Heart Program, Smidt Heart Institute, Los Angeles, California.

Congenital Heart Disease
|February 28, 2019
PubMed

Insights

Patent ductus arteriosus (PDA) causes illness in premature infants. Transcatheter PDA closure is a new, viable treatment option for extremely low birth weight infants, offering an alternative to surgery.

Area of Science:

  • Neonatal cardiology
  • Pediatric cardiovascular interventions
  • Perinatal medicine

Background:

  • Patent ductus arteriosus (PDA) is a common complication in extremely low birth weight (ELBW) infants.
  • Significant morbidity is associated with hemodynamically significant PDA in this vulnerable population.
  • Current management strategies include supportive care, pharmacotherapy, and surgical ligation, each with limitations.

Purpose of the Study:

  • To provide a comprehensive review of transcatheter PDA closure.
  • To evaluate transcatheter PDA closure as an emerging and viable option for ELBW infants.
  • To discuss the advantages and limitations of various PDA management strategies.

Main Methods:

  • Literature review of transcatheter PDA closure in ELBW infants.
  • Analysis of current management approaches for PDA in neonates.
  • Synthesis of data on the efficacy and safety of transcatheter interventions.

Main Results:

  • Transcatheter PDA closure has emerged as a promising alternative to traditional therapies.
  • This minimally invasive approach offers potential benefits for ELBW infants with PDA.
  • The review consolidates current understanding of this evolving procedure.

Conclusions:

  • Transcatheter PDA closure represents a significant advancement in managing PDA in ELBW infants.
  • Further research and experience are crucial to optimize this technique.
  • This approach may reduce the morbidity associated with PDA in premature neonates.

Keywords:
device occlusionextremely low birth weight infantpatent ductus arteriosus

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