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Related Experiment Video

Updated: Jan 28, 2026

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A comprehensive program for preterm infants with patent ductus arteriosus.

Leah Apalodimas1, Benjamin Rush Waller Iii1, Ranjit Philip1

  • 1Department of Pediatric Cardiology, University of Tennessee Health Science Center, LeBonheur Children's Hospital, Memphis, Tennessee.

Congenital Heart Disease
|February 28, 2019
PubMed
Summary

Transcatheter PDA closure (TCPC) offers a safe and effective treatment for preterm infants with patent ductus arteriosus (PDA). A specialized clinic ensures optimal post-discharge follow-up, improving long-term outcomes for these vulnerable infants.

Keywords:
extremely low birth weightneonatologyneurodevelopmental outcomespatent ductus arteriosuspediatricspreterm infanttranscatheter PDA closure

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Area of Science:

  • Neonatal Cardiology
  • Pediatric Interventional Cardiology
  • Neonatal Intensive Care

Background:

  • Patent ductus arteriosus (PDA) is a common condition in preterm infants, potentially requiring intervention.
  • Hemodynamically significant PDAs can impact infant health and require timely management.

Purpose of the Study:

  • To describe a transcatheter PDA closure (TCPC) program tailored for preterm infants.
  • To outline a comprehensive outpatient follow-up strategy for infants undergoing TCPC.

Main Methods:

  • A multidisciplinary team approach was utilized for the care of extremely low birth weight (ELBW) infants.
  • TCPC was performed on 134 ELBW infants, with detailed follow-up managed by the Memphis PDA Clinic.
  • Outcomes were assessed based on respiratory support, enteral feeding tolerance, growth, and neurodevelopmental progress.

Main Results:

  • TCPC facilitated faster ventilator weaning, improved enteral feeding tolerance, and enhanced somatic growth in ELBW infants.
  • The Memphis PDA Clinic successfully provided optimal post-discharge follow-up, contributing to improved long-term outcomes.
  • TCPC led to a shorter overall hospital length of stay.

Conclusions:

  • Transcatheter PDA closure (TCPC) is a safe and effective intervention for hemodynamically significant PDAs in ELBW infants.
  • A dedicated multispecialty clinic for post-discharge follow-up is crucial for improving outcomes in this population.