Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

What is an Electrochemical Gradient?01:26

What is an Electrochemical Gradient?

127.7K
Adenosine triphosphate, or ATP, is considered the primary energy source in cells. However, energy can also be stored in the electrochemical gradient of an ion across the plasma membrane, which is determined by two factors: its chemical and electrical gradients.
The chemical gradient relies on differences in the abundance of a substance on the outside versus the inside of a cell and flows from areas of high to low ion concentration. In contrast, the electrical gradient revolves around an...
127.7K
The Sense of Self: Reflected Self-Appraisal and Social Comparison02:57

The Sense of Self: Reflected Self-Appraisal and Social Comparison

56.0K
According to Charles Cooley, we base our image on what we think other people see (Cooley 1902). We imagine how we must appear to others, then react to this speculation. We don certain clothes, prepare our hair in a particular manner, wear makeup, use cologne, and the like—all with the notion that our presentation of ourselves is going to affect how others perceive us. We expect a certain reaction, and, if lucky, we get the one we desire and feel good about it. But more than that, Cooley...
56.0K
Introduction to Special Senses01:26

Introduction to Special Senses

7.5K
Sensory receptors play an integral part in comprehending our external and internal environments. They receive diverse stimuli, converting them into the nervous system's electrochemical signals. This conversion occurs as the stimulus alters the sensory neuron's cell membrane potential, instigating the generation of an action potential. This action potential is subsequently transmitted to the central nervous system (CNS), which integrates with other sensory data or higher cognitive...
7.5K
Tactile and Chemical Senses01:27

Tactile and Chemical Senses

791
Tactile senses encompass touch, temperature, and pain, each mediated by specific receptors. Touch receptors detect mechanical energy or pressure against the skin. Sensory fibers from these receptors enter the spinal cord and relay information to the brain stem. Here, most fibers cross over to the opposite side of the brain. The touch information then moves to the thalamus, which projects a map of the body's surface onto the somatosensory areas of the parietal lobes in the cerebral cortex.
791
Interfacial Electrochemical Methods: Overview01:06

Interfacial Electrochemical Methods: Overview

864
Interfacial electrochemical methods focus on the phenomena occurring at the boundary between an electrode and a solution, as opposed to bulk methods that concentrate on the solution's overall properties. These interfacial methods are classified as either static or dynamic based on the presence of a nonzero current in the electrochemical cell and the consistency of analyte concentrations. Static methods, such as potentiometry, measure the cell's potential without any significant current...
864
Electrochemical Gradient and Channel Proteins: An Overview01:21

Electrochemical Gradient and Channel Proteins: An Overview

4.7K
An electrochemical gradient is a fundamental concept in biology and chemistry. It regulates the movement of ions across cell membranes. This movement is influenced by two factors:
The electrical gradient: The electrical gradient across cell membranes refers to the difference in electric charge between the inside and outside of a cell.  This difference drives the movement of ions towards or away from the cells. For instance, if the inside of the cell is more negatively charged relative to...
4.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Complement Inhibition in the Clinic: Are We Doing Enough to Protect Patients From Infection?

European journal of immunology·2026
Same author

Irinotecan-Loaded Vaterite Microspheres for Drug Delivery: Drug Release and Dissolution Kinetics and Mechanism in an Aqueous Solution and Human Serum.

Langmuir : the ACS journal of surfaces and colloids·2026
Same author

Spicy Electrochemistry: Quantifying Chili Heat as a Didactic Approach to Incorporate Electroanalysis into the Undergraduate Curriculum.

Journal of chemical education·2026
Same author

Hemiconvulsion-hemiplegia-epilepsy syndrome in a child with an underlying hypomyelinating leukodystrophy: a previously unreported association.

Pediatric radiology·2026
Same author

Tracking carboplatin chemoresistance in ovarian cancer by scanning electrochemical microscopy.

Chemical science·2025
Same author

Insights into the antioxidant activity of carotenoid standards, microalgal, and yeast extracts via spectroscopic and electrochemical methods.

Food chemistry·2025

Related Experiment Video

Updated: Jan 28, 2026

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
08:19

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Published on: June 1, 2012

15.0K

Versatile Electrochemical Sensing Platform for Bacteria.

Sabine Kuss1,2, Rosa A S Couto3, Rhiannon M Evans4

  • 1Department of Chemistry , University of Oxford , South Parks Road , Oxford OX1 3QZ , United Kingdom.

Analytical Chemistry
|February 28, 2019
PubMed
Summary

This study introduces a novel electrochemical biosensor for rapid, selective, and cost-efficient detection of bacterial infections. The device identifies pathogens like E. coli and N. gonorrheae within seconds, offering a significant advance in diagnostic technology.

More Related Videos

Self-standing Electrochemical Set-up to Enrich Anode-respiring Bacteria On-site
05:29

Self-standing Electrochemical Set-up to Enrich Anode-respiring Bacteria On-site

Published on: July 24, 2018

8.1K
A Versatile Automated Platform for Micro-scale Cell Stimulation Experiments
12:21

A Versatile Automated Platform for Micro-scale Cell Stimulation Experiments

Published on: August 6, 2013

11.0K

Related Experiment Videos

Last Updated: Jan 28, 2026

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
08:19

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Published on: June 1, 2012

15.0K
Self-standing Electrochemical Set-up to Enrich Anode-respiring Bacteria On-site
05:29

Self-standing Electrochemical Set-up to Enrich Anode-respiring Bacteria On-site

Published on: July 24, 2018

8.1K
A Versatile Automated Platform for Micro-scale Cell Stimulation Experiments
12:21

A Versatile Automated Platform for Micro-scale Cell Stimulation Experiments

Published on: August 6, 2013

11.0K

Area of Science:

  • Biomedical Engineering
  • Analytical Chemistry
  • Microbiology

Background:

  • Bacterial infections are a major global health concern, necessitating rapid and accurate diagnostic tools.
  • Current detection methods often lack the required sensitivity, selectivity, or ease of use for widespread application.
  • There is an urgent need for advanced biosensing technologies to combat infectious diseases.

Purpose of the Study:

  • To develop a novel electrochemical biosensor for the rapid and selective detection of pathogenic bacteria.
  • To demonstrate the biosensor's efficacy using clinically relevant bacterial species such as Escherichia coli and Neisseria gonorrheae.
  • To establish a versatile platform applicable to a broad range of bacterial pathogens.

Main Methods:

  • An electrochemical biosensor was designed utilizing the bacterial enzyme cytochrome c oxidase as a detection marker.
  • The biosensor involved the immobilization of target pathogens and electrochemical detection of enzyme activity.
  • The system was tested for selectivity and sensitivity against specific bacterial strains.

Main Results:

  • The electrochemical biosensor achieved selective detection of Escherichia coli and Neisseria gonorrheae within seconds.
  • Clinically relevant concentrations of bacteria were detected with high sensitivity.
  • The biosensor demonstrated applicability to portable devices using screen-printed electrodes.

Conclusions:

  • The developed electrochemical biosensor offers a sensitive, selective, and rapid method for bacterial detection.
  • The platform's adaptability, leveraging cytochrome c oxidase and interchangeable antibodies, supports broad pathogen applicability.
  • This technology shows promise for portable, cost-efficient diagnostics in clinical settings and beyond.