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Updated: Jan 28, 2026

A Quantitative Assay to Study Protein:DNA Interactions, Discover Transcriptional Regulators of Gene Expression, and Identify Novel Anti-tumor Agents
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Specificity from nonspecific interaction: regulation of tumor necrosis factor-α activity by DNA

Helena Andrade1, Weilin Lin1, Yixin Zhang2

  • 1From the B CUBE Center for Molecular Bioengineering, Technische Universität Dresden, 01307 Dresden, Germany.

The Journal of Biological Chemistry
|March 1, 2019
PubMed

Keywords:
DNA–protein interactionactivity regulationallosteric regulationbiolayer interferometrycircular dichroism (CD)homoquenchingnonspecific interactionphoto-switchable proteinprotein–nucleic acid interactiontumor necrosis factor (TNF)

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