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Updated: Jan 28, 2026
06:15
Use of Bisection to Reduce Mitochondrial DNA in the Bovine Oocyte
Published on: July 6, 2022
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Author Correction: Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations
Eunju Kang1,2,3, Jun Wu4, Nuria Marti Gutierrez1,2
1Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, Oregon, 97239, USA.
Nature
|March 1, 2019
Summary
Mitochondrial DNA (mtDNA) haplotype assignments for egg donors in this study contain errors. These inaccuracies in genetic data have not yet been rectified in the online publication.
Area of Science:
- Genetics
- Molecular Biology
- Reproductive Science
Context:
- Mitochondrial DNA (mtDNA) analysis is crucial for genetic studies, including those involving assisted reproduction.
- Accurate haplotype assignment is essential for reliable genetic research and donor selection.
Purpose:
- To acknowledge and report errors in the assignment of mitochondrial DNA (mtDNA) haplotypes for a subset of egg donors.
- To inform readers about the presence of uncorrected data in the published letter.
Summary:
- A subset of egg donor mitochondrial DNA (mtDNA) haplotypes were incorrectly assigned in the original publication.
- These specific data errors pertain to the genetic profiles of some egg donors utilized in the study.
Impact:
- Readers should be aware of these data inaccuracies when interpreting the study's findings related to egg donor genetics.
- The uncorrected errors may affect the reproducibility and application of the study's genetic conclusions.
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