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Sex Differences in Mouse Hippocampal Astrocytes after In-Vitro Ischemia
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Sex Differences in Human Olfaction: A Meta-Analysis.

Piotr Sorokowski1, Maciej Karwowski1, Michał Misiak1

  • 1Institute of Psychology, University of Wroclaw, Wroclaw, Poland.

Frontiers in Psychology
|March 1, 2019
PubMed
Summary

Women generally have better olfactory abilities than men, confirmed by a meta-analysis of large-scale studies. However, these sex differences in smell perception are small.

Keywords:
SSTUPSITmeta-analysisolfactionsex differences

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Area of Science:

  • Neuroscience
  • Sensory Science
  • Human Biology

Background:

  • Common belief suggests women possess superior olfactory abilities compared to men.
  • Previous large-scale studies have indicated similar olfactory performance between sexes, creating a discrepancy.

Purpose of the Study:

  • To resolve conflicting findings regarding sex differences in olfactory abilities.
  • To conduct a meta-analysis examining sex-based variations in smell identification, discrimination, and threshold.

Main Methods:

  • A comprehensive meta-analysis was performed on existing olfaction studies.
  • Data from thousands of participants (over 8,000 for threshold, 8,000 for discrimination, 13,000 for identification) were analyzed.
  • Separate meta-analyses were conducted for olfactory identification, discrimination, and threshold using Sniffin Sticks Test (SST) and University of Pennsylvania Smell Identification Test (UPSIT).

Main Results:

  • Women consistently outperformed men across all analyzed aspects of olfaction: identification, discrimination, and threshold.
  • The meta-analysis revealed statistically significant, yet small, effect sizes for these differences, ranging from g = 0.08 to g = 0.30.
  • The findings support the notion of female olfactory superiority, but with minimal practical effect size.

Conclusions:

  • The study confirms a general, albeit small, female advantage in olfactory abilities.
  • The observed sex differences in olfaction are statistically significant but weak.
  • Further research is needed to explore factors contributing to these subtle sex differences in smell perception.