Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Local Anesthetics: Clinical Application as Epidural Anesthesia01:29

Local Anesthetics: Clinical Application as Epidural Anesthesia

718
Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
718
General Anesthesia: Overview01:24

General Anesthesia: Overview

651
Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
651
Stages of General Anesthesia01:22

Stages of General Anesthesia

1.6K
Various sedation levels offer significant advantages in facilitating procedural interventions for patients undergoing medical or invasive surgical procedures. These levels span from anxiolysis to general anesthesia, providing a spectrum of sedative effects to cater to specific patient needs. Anxiolysis reduces anxiety and is achieved through minimal sedation, enabling patients to remain awake and responsive while feeling more at ease during the procedure. This level can benefit minor...
1.6K
Local Anesthetics: Clinical Application as Spinal Anesthesia01:11

Local Anesthetics: Clinical Application as Spinal Anesthesia

1.4K
Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
1.4K
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia01:16

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

1.3K
Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
1.3K
Blind Procedures02:07

Blind Procedures

13.4K
Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...
13.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Data-Driven Evidence-Based Patient-Centered Optimal Initiation Time for Dialysis Treatment.

AMIA ... Annual Symposium proceedings. AMIA Symposium·2026
Same author

Data-Driven Approach to Design an Efficient Mass Vaccination and Public Health Monitoring Informatics Platform.

AMIA ... Annual Symposium proceedings. AMIA Symposium·2026
Same author

Temporal and spatial analysis of over 7,000 measles cases outbreak from 2018 to 2019 in the Brazilian Amazon.

Einstein (Sao Paulo, Brazil)·2024
Same author

New PK/PD model directly links diabetes drug dose to blood glucose level for personalized care.

AMIA ... Annual Symposium proceedings. AMIA Symposium·2023
Same author

Analyzing Strategies for Containing Avian Influenza.

AMIA ... Annual Symposium proceedings. AMIA Symposium·2023
Same author

Spatial clustering of heroin-related overdose incidents: a case study in Cincinnati, Ohio.

BMC public health·2022
Same journal

Sensitivity Analyses of a Scoring System for a Contraception Decision Aid.

AMIA ... Annual Symposium proceedings. AMIA Symposium·2026
Same journal

Improving electronic health record processing of large language models via retrieval-augmented generation: A case study on dietary supplements.

AMIA ... Annual Symposium proceedings. AMIA Symposium·2026
Same journal

Developing a User-Centered Mobile Application Prototype: Bridging Lower-Limb Fracture Care from Skilled Nursing Facility and Back to the Community.

AMIA ... Annual Symposium proceedings. AMIA Symposium·2026
Same journal

KERAP: A Knowledge-Enhanced Reasoning Approach for Accurate Zero-shot Diagnosis Prediction Using Multi-agent LLMs.

AMIA ... Annual Symposium proceedings. AMIA Symposium·2026
Same journal

Automating Adjudication of Cardiovascular Events Using Large Language Models.

AMIA ... Annual Symposium proceedings. AMIA Symposium·2026
Same journal

Predictive Factors and State-Level Barriers to Postpartum Birth Control Usage in the United States: Insights from PRAMS Phase 8.

AMIA ... Annual Symposium proceedings. AMIA Symposium·2026
See all related articles

Related Experiment Video

Updated: Jan 28, 2026

Systematic Assessment of Well-Being in Mice for Procedures Using General Anesthesia
06:50

Systematic Assessment of Well-Being in Mice for Procedures Using General Anesthesia

Published on: March 20, 2018

12.9K

Investigating a Needle-Based Epidural Procedure in Obstetric Anesthesia.

Eva K Lee1,2,3, Haozheng Tian1,2,3, Jinha Lee1,2,3

  • 1NSF-Whitaker Center for Operations Research in Medicine and HealthCare.

AMIA ... Annual Symposium Proceedings. AMIA Symposium
|March 1, 2019
PubMed
Summary
This summary is machine-generated.

A novel needle-based epidural technique in obstetric anesthesia is faster and more dose-effective. Large doses are safe, and machine learning predicts lower hypotension rates with doses under 18 ml.

More Related Videos

Author Spotlight: Exploring the Impact of Lingnan Fire-Needle Therapy in Osteoporosis Intervention
03:56

Author Spotlight: Exploring the Impact of Lingnan Fire-Needle Therapy in Osteoporosis Intervention

Published on: April 26, 2024

1.3K
External Cephalic Version: Is it an Effective and Safe Procedure?
08:49

External Cephalic Version: Is it an Effective and Safe Procedure?

Published on: June 6, 2020

15.8K

Related Experiment Videos

Last Updated: Jan 28, 2026

Systematic Assessment of Well-Being in Mice for Procedures Using General Anesthesia
06:50

Systematic Assessment of Well-Being in Mice for Procedures Using General Anesthesia

Published on: March 20, 2018

12.9K
Author Spotlight: Exploring the Impact of Lingnan Fire-Needle Therapy in Osteoporosis Intervention
03:56

Author Spotlight: Exploring the Impact of Lingnan Fire-Needle Therapy in Osteoporosis Intervention

Published on: April 26, 2024

1.3K
External Cephalic Version: Is it an Effective and Safe Procedure?
08:49

External Cephalic Version: Is it an Effective and Safe Procedure?

Published on: June 6, 2020

15.8K

Area of Science:

  • Anesthesiology
  • Obstetric Anesthesia
  • Epidural Techniques

Background:

  • Standard epidural anesthesia uses a catheter-based approach.
  • A novel needle-based technique involves administering anesthetic dose via needle before catheter insertion.

Purpose of the Study:

  • To investigate the safety and efficacy of a large-dose, needle-based epidural technique in obstetric anesthesia.
  • To compare this technique with the standard catheter-based approach.
  • To utilize informatics and machine learning for data analysis.

Main Methods:

  • Employed a data-driven informatics and machine learning approach.
  • Administered anesthetic dose through an epidural needle prior to catheter insertion.
  • Analyzed complication rates and hypotension incidence.

Main Results:

  • The needle-based technique is faster and more dose-effective for achieving sensory level.
  • Injecting large doses via the epidural needle is safe, with complication rates comparable to catheter-based techniques.
  • Machine learning predicts significantly lower hypotension rates if the needle dose is under 18 ml (85% accuracy).

Conclusions:

  • The needle-based epidural technique is a safe and effective alternative in obstetric anesthesia.
  • This technique offers improved speed and dose-effectiveness.
  • Machine learning can guide clinical practice to minimize hypotension, enhancing patient safety and improving delivery outcomes.