Related Experiment Video
Updated: Jan 28, 2026

Burn Injury-Induced Pain and Depression-Like Behavior in Mice
Published on: September 29, 2021
Short Runs for a Long Slide: Principalization in Complex Facial Restoration after Acid Attack Burn Injury
Christopher D Hughes1,2, Robert Jaroslaw Dabek1, Johanna N Riesel1
1Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Boston, Massachusetts.
Abstract:
Burn injuries are responsible for a significant portion of surgically treatable morbidity throughout the world and particularly in underdeveloped and developing countries. Intentional flame, chemical, and contact burns are unfortunately a common mechanism of injury. It is estimated that intentional chemical burns are responsible for between 2 and 20% of burn injuries seen at burn centers in lower income countries. Women are commonly targeted and the perpetrators are often known to the victims. The combination of a high disease prevalence, limited surgical and anesthetic resources, a vulnerable patient population, and largely disfiguring, nonlethal injuries present unique challenges for the reconstructive surgeon who may not encounter such cases regularly. In this article, we present a case of a 16-year-old female who sustained severe, full-thickness burns to the face including eyelids, neck, abdomen, and upper extremities after an intentional acid attack. She began her treatment course with us approximately 1 year after the injury. The deformities of her oral and periorbital regions presented particularly difficult reconstructive problems, including impending visual loss. Using plastic surgical principalization, we provided our patient adequate restoration of facial form and function through numbers of interventions using fundamental and state-of-the-art techniques.
Related Concept Videos
Burn Injuries
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
Acid Attack on Concrete
The rate at which hydrogen...
Principal Stresses in a Beam
Analyzing principal stresses is crucial, especially in...
Restorative Care
Principal Moments of Area
The principal moment of inertia axes are the...
Principal Stresses

