Atraumatic splenic rupture associated with apixaban

Sijan Basnet1, Elan Mohanty1, Izza Mir1

  • 1Department of Medicine, Reading Hospital and Medical Center, West Reading, PA, USA.

Apixaban is a direct oral anticoagulant that works by inhibiting factor Xa. It has been associated with adverse bleeding outcomes including atraumatic splenic rupture. We present the case of an 86-year-old man who presented with features of left upper abdominal pain and hemorrhagic shock found to have atraumatic splenic rupture and hemoperitoneum on imaging.