Effect of bariatric surgery before pregnancy on the vascular function in the offspring: protocol of a cross-sectional

Related Experiment Video

Updated: Jan 28, 2026

Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus
06:55

Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus

Published on: December 5, 2015

14.1K

Karolien Van De Maele1,2, Inge Gies1, Roland Devlieger2,3

  • 1Department of Pediatrics, Division of Pediatric Endocrinology, Universitair Ziekenhuis Brussel, Brussels, Belgium.

BMJ Paediatrics Open
|March 1, 2019
PubMed

Insights

Maternal weight management before and during pregnancy significantly impacts offspring cardiovascular health. This study investigates long-term cardiovascular programming in children based on maternal weight status and interventions.

Area of Science:

  • Pediatric Cardiology
  • Metabolic Health
  • Maternal Health

Background:

  • Offspring of obese mothers face risks of metabolic, inflammatory, and cardiovascular issues.
  • Long-term data on maternal weight changes' impact on offspring cardiovascular programming are limited.

Purpose of the Study:

  • To assess the long-term cardiovascular programming in children based on maternal pre-pregnancy weight and interventions.
  • To compare the effects of bariatric surgery versus lifestyle interventions on offspring cardiovascular health.

Main Methods:

  • Cross-sectional cohort follow-up study of children from previously studied pregnancies.
  • Four subgroups: children of normal weight, obese, lifestyle-intervention, and bariatric surgery mothers.
  • Data includes questionnaires, anthropometry, bioimpedance, ultrasound, endothelial function (EndoPAT), and biomarkers.

Main Results:

  • N/A - Study is pre-results.

Conclusions:

  • N/A - Study is pre-results.
Abstract

Keywords:
endocrinologymetabolicobesityvascular disease

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