Related Experiment Video
Updated: Jan 28, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
[Blisters and skin abnormality after playing in the garden]
Astrid A M Heijthuijsen1,2, Karlijn Sijstermans1, Michiel Appelman3
1Onze Lieve Vrouwe Gasthuis, afd. Kindergeneeskunde, Amsterdam.
Abstract:
On a sunny day, a 2-year-old boy came to the paediatric department with skin abnormalities. These had started as redness and blisters and later also included hyperpigmentation. He had played near a phototoxic plant known as 'common rue' (Ruta graveolens). Our diagnosis was phytophotodermatitis caused by the common rue.
Related Concept Videos
Abnormal Proliferation
Social Foundations of Self I: Play and Game
Respiratory System Abnormal Finding I: Inspection and Percussion
Inspection Findings
During an inspection, several findings may suggest the presence of respiratory distress or disease. Pursed-lip breathing, where exhalation is slowed by...
Cardiovascular System Abnormal Findings I: Inspection and Palpation
Abnormal findings observed during an inspection
Cardiovascular System Abnormal Findings II: Auscultation
Abnormal Heart Sounds
Gallops:
Respiratory System Abnormal Finding II: Palpation and Auscultation
Palpation Findings
During a respiratory assessment, palpation can reveal several vital abnormalities:

