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Compartmentalized regulation of macrophage arachidonic acid metabolism

A O Fels, N A Pawlowski, E L Abraham

The Journal of Experimental Medicine

|March 1, 1986

Abstract:

We show that downregulation of arachidonic acid (20:4) metabolism which occurs following i.p. injection of C. parvum can occur in a single, localized macrophage population, and is therefore unlikely to be mediated solely by a systemic factor.

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