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Low mortality and short-term morbidity in very preterm infants in Austria 2011-2016

U Kiechl-Kohlendorfer1, B Simma2, B Urlesberger3

  • 1Department of Paediatrics II (Neonatology), Medical University of Innsbruck, Innsbruck, Austria.

Acta Paediatrica (Oslo, Norway : 1992)
|March 1, 2019
PubMed

Insights

Survival rates for very preterm infants in Austria are high, with low short-term morbidity. Key predictors for adverse outcomes include low gestational age and male sex.

Area of Science:

  • Neonatalogy
  • Pediatric Medicine
  • Public Health

Background:

  • Preterm birth presents significant challenges for infant survival and health.
  • Understanding outcomes in very preterm infants is crucial for improving neonatal care.
  • Austria's national data provides a valuable resource for studying preterm infant populations.

Purpose of the Study:

  • To determine survival rates in very preterm infants in Austria.
  • To assess short-term neonatal morbidity among this population.
  • To identify predictors of death or adverse outcomes in very preterm infants.

Main Methods:

  • A population-based cohort study utilizing the Austrian Preterm Outcome Registry.
  • Inclusion of 5197 very preterm infants born between 2011 and 2016.
  • Analysis of gestational age-related mortality and major short-term morbidities.

Main Results:

  • Overall survival rate was 91.6%, with survival increasing significantly with gestational age (e.g., >90% for ≥27 weeks).
  • Prevalence of major morbidities: chronic lung disease (10.0%), necrotizing enterocolitis (2.1%), severe intraventricular hemorrhage (5.5%), and severe retinopathy of prematurity (3.6%).
  • Significant risk predictors for adverse outcomes included low gestational age, low birth weight, incomplete antenatal steroids, male sex, and multiple births.

Conclusions:

  • The national cohort study demonstrated high overall survival rates for very preterm infants in Austria.
  • Short-term morbidity rates were found to be low in this population.
  • Identifying risk factors aids in targeted interventions and improved neonatal care strategies.
Abstract

Keywords:
Preterm infantsShort-term outcomeSurvival

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