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Updated: Jan 28, 2026

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Published on: April 23, 2021
Multimodal Nutritional Management in Primary Lumbar Spine Surgery: A Randomized Controlled Trial
Bin Xu1, Wei-Xing Xu, Yang-Jun Lao
1Department of Orthopaedics, Tongde Hospital of Zhejiang Province, Hangzhou, People's Republic of China.
A new multimodal nutritional management (MNM) protocol improved recovery for lumbar spine surgery patients by reducing albumin infusions and electrolyte imbalances. This enhanced recovery pathway led to shorter hospital stays and less wound drainage without increasing complications.
Area of Science:
- Orthopedic Surgery
- Surgical Nutrition
- Patient Recovery
Background:
- Perioperative malnutrition is prevalent in primary lumbar spine surgery patients.
- Poor nutritional status can negatively impact surgical recovery outcomes.
Purpose of the Study:
- To assess the clinical efficacy and safety of a novel multimodal nutritional management (MNM) protocol.
- To evaluate MNM's impact on patients undergoing primary lumbar spine surgery.
Main Methods:
- A prospective randomized controlled trial involving 187 patients.
- Patients were randomized into either the MNM group or a control group.
- Key metrics included albumin infusion, postoperative albumin levels, electrolyte balance, transfusion rates, hemoglobin, length of stay, and complications.
Main Results:
- The MNM group showed reduced albumin infusion and higher postoperative albumin levels.
- Lower incidence of hypokalemia, hyponatremia, and hypocalcemia was observed in the MNM group.
- Shorter length of stay and reduced wound drainage were noted in the MNM group, with similar complication rates.
Conclusions:
- The MNM protocol effectively optimizes nutritional status and reduces complications.
- MNM improves key recovery markers, including electrolyte balance and length of stay.
- This protocol offers a safe and effective approach to perioperative nutritional management in lumbar spine surgery.
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