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Updated: Jan 28, 2026

Non-enzymatic, Serum-free Tissue Culture of Pre-invasive Breast Lesions for Spontaneous Generation of Mammospheres
Published on: November 8, 2014
Preoperative localization of breast lesions: Current techniques
Ray C Mayo1, Megan J Kalambo1, Jay R Parikh1
1Department of Radiology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe, CPB 5.3208, Houston, TX, USA.
Preoperative breast lesion localization using imaging guidance is crucial. This review compares wire, radioactive seed, radiofrequency reflector, and magnetic seed methods, aiding radiologists in choosing optimal techniques for patient-centered care.
Area of Science:
- Radiology
- Surgical Oncology
- Medical Devices
Background:
- Image-guided preoperative localization of breast lesions is a standard procedure.
- Accurate localization is essential for successful surgical excision and diagnosis.
Purpose of the Study:
- To review and compare commercially available image-guided preoperative breast lesion localization techniques.
- To outline the advantages and disadvantages of each method.
Main Methods:
- Comparative review of wire localization, radioactive seed localization, radiofrequency reflector localization, and magnetic seed localization.
- Discussion of the benefits and drawbacks of each technique.
Main Results:
- Each localization method (wire, radioactive seed, radiofrequency reflector, magnetic seed) offers distinct advantages and disadvantages.
- The choice of method depends on clinical context and institutional resources.
Conclusions:
- Radiologists can use this information to guide discussions with surgical and administrative teams.
- Selecting the appropriate localization technique can enhance value and patient care.
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