Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fetal lung fluid response to maternal hyperosmolality.

M G Ross, R D Leake, M G Ervin

    Pediatric Pulmonology
    |January 1, 1986
    PubMed
    Summary

    Fetal lambs reduce lung fluid production when osmolality increases, a response mediated by arginine vasopressin. This finding is crucial for understanding fetal development and stress responses in utero.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Development of a paw paw herbal shampoo for the removal of head lice.

    Phytomedicine : international journal of phytotherapy and phytopharmacology·2003
    Same author

    An audit of the use of granulocyte colony-stimulating factor in septic shock.

    Internal medicine journal·2002
    Same author

    Neonatal thyroid enlargement associated with propylthiouracil therapy of Graves' disease during pregnancy: a problem revisited.

    The Journal of pediatrics·2001
    Same author

    The state and future of Mars polar science and exploration.

    Icarus·2001
    Same author

    3,3'-Diiodothyronine sulfate excretion in maternal urine reflects fetal thyroid function in sheep.

    Pediatric research·2001
    Same author

    Court procedures for handling intoxicated drivers.

    Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism·2001

    Area of Science:

    • Reproductive Physiology
    • Fetal Development
    • Endocrinology

    Background:

    • Lung fluid production is a major source of amniotic fluid.
    • Fetal responses to environmental stress are not fully understood.
    • Arginine vasopressin plays a role in fluid balance.

    Purpose of the Study:

    • To investigate the regulation of fetal lung fluid production in response to maternal hyperosmolality.
    • To determine the role of arginine vasopressin in this response.

    Main Methods:

    • Chronic catheterization of ovine fetuses to monitor physiological parameters.
    • Mannitol infusion to induce maternal and fetal hyperosmolality.
    • Measurement of plasma osmolality, arginine vasopressin levels, and fetal lung fluid production.

    Main Results:

    • Maternal and fetal hyperosmolality significantly decreased fetal lung fluid production.
    • Fetal lung fluid osmolality increased, while sodium and potassium concentrations remained unchanged.
    • Fetal plasma arginine vasopressin levels significantly increased in response to hyperosmolality.

    Conclusions:

    • Fetal lambs decrease lung fluid production under hyperosmotic conditions.
    • Increased fetal plasma arginine vasopressin levels mediate this response.
    • This mechanism highlights fetal adaptation to osmotic stress.

    Related Experiment Videos