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Updated: Jan 28, 2026

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
Published on: July 19, 2019
[Ejaculation disorders in multiple sclerosis: Prospective study of 44 patients].
C Blum1, C Chesnel2, C Hentzen2
1GRC 01, Green - groupe de recherche clinique en neuro-urologie, Sorbonne universités, AP-HP, hôpital Tenon, 75020 Paris, France; Institut universitaire de réadaptation Clemenceau (IURC), 45, boulevard Clemenceau, 67000 Strasbourg, France; Service de neuro-urologie, hôpital Tenon, 4, rue de la Chine, 75020 Paris, France.
Ejaculation disorders, including decreased volume and delayed ejaculation, affect 64% of men with multiple sclerosis (MS). These sexual health issues correlate with erectile dysfunction but not with urinary or anorectal problems in MS patients.
Area of Science:
- Neurology
- Urology
- Sexual Medicine
Background:
- Multiple sclerosis (MS) can significantly impact men's sexual health.
- Ejaculation disorders are common but often underreported in MS patients.
Purpose of the Study:
- To descriptively analyze ejaculation disorders in men with MS.
- To investigate correlations between dysejaculations and other sexual, urinary, and anorectal disorders.
Main Methods:
- Prospective, monocentric, non-interventional study.
- Ejaculation disorders assessed using Premature Ejaculation Profile (PEP) and Male Sexual Health Questionnaire-Ejaculation (MSHQ-Ej) scores.
- Sexual, urinary, and anorectal function evaluated with International Index of Erectile Function (IIEF15) and MSISQ.
Main Results:
- 64% of 44 MS patients (mean age 46.8) experienced ejaculation disorders.
- Common issues included decreased ejaculated volume (55%), decreased ejaculation flow (59%), and delayed ejaculation (52%).
- A significant correlation was found between ejaculation disorders and erectile dysfunction (r=0.53, P<0.05), but not with urinary or anorectal disorders.
Conclusions:
- Dysejaculation is highly prevalent (64%) in men with MS.
- Key characteristics of dysejaculation in MS include reduced ejaculated volume, weaker ejaculation, and delayed ejaculation.
- Ejaculation disorders in MS are significantly associated with erectile dysfunction.
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