Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Rates of DNA sequence evolution differ between taxonomic groups.

R J Britten

    Science (New York, N.Y.)
    |March 21, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    SEA URCHIN DNA SEQUENCE VARIATION AND REDUCED INTERSPECIES DIFFERENCES OF THE LESS VARIABLE DNA SEQUENCES.

    Evolution; international journal of organic evolution·2017
    Same author

    Climate change and the integrity of science.

    Science (New York, N.Y.)·2010
    Same author

    The Synthesis of Ribosomes in E. coli: I. The Incorporation of C-Uracil into the Metabolic Pool and RNA.

    Biophysical journal·2009
    Same author

    The Synthesis of Ribosomes in E. coli: III. Synthesis of Ribosomal RNA.

    Biophysical journal·2009
    Same author

    Identification of new skeletogenic genes of the sea urchin embryo by use of conserved sequence motifs among the SM50 gene family.

    Zygote (Cambridge, England)·2001
    Same author

    A sea urchin genome project: sequence scan, virtual map, and additional resources.

    Proceedings of the National Academy of Sciences of the United States of America·2000
    Same journal

    Erratum for the Research Article "Detecting supramolecular organic nanoparticles during heat wave".

    Science (New York, N.Y.)·2026
    Same journal

    Local signals, systemic decline.

    Science (New York, N.Y.)·2026
    Same journal

    The mechanics of liver regeneration.

    Science (New York, N.Y.)·2026
    Same journal

    Computing in a memory with physics.

    Science (New York, N.Y.)·2026
    Same journal

    Retraction.

    Science (New York, N.Y.)·2026
    Same journal

    Making time.

    Science (New York, N.Y.)·2026
    See all related articles

    Evolutionary DNA mutation rates vary significantly across species, with primates showing slower rates than rodents. These differences are likely due to variations in DNA repair and replication mechanisms.

    Area of Science:

    • Evolutionary biology
    • Molecular evolution
    • Genetics

    Background:

    • Mutation rates are crucial for understanding evolutionary divergence.
    • Estimating neutral mutation rates uses interspecies DNA sequence differences.
    • Previous studies indicate variability in evolutionary rates across taxa.

    Purpose of the Study:

    • To analyze and compare DNA sequence change rates across diverse phylogenetic groups.
    • To investigate the trend of mutation rate changes within primate evolution.
    • To explore potential molecular mechanisms underlying observed rate variations.

    Main Methods:

    • Analysis of existing DNA sequence data from various species.
    • Calculation of neutral mutation rates based on interspecies sequence differences.

    Related Experiment Videos

  • Comparative analysis of mutation rates across different evolutionary lineages.

    • Main Results:

    • Observed a five-fold difference in DNA change rates among phylogenetic groups.
    • Identified slower mutation rates in higher primates and some bird lineages.
    • Detected faster mutation rates in rodents, sea urchins, and drosophila.
    • Noted a significant decrease in DNA sequence change rate during primate evolution.

    Conclusions:

    • Significant variation in evolutionary DNA mutation rates exists across the tree of life.
    • Primate evolution exhibits a decelerating rate of DNA sequence change.
    • Biochemical mechanisms, including DNA replication and repair, are likely drivers of these evolutionary rate differences.