Related Experiment Video
Updated: Jan 28, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
Medication persistence for psoriatic arthritis in a Brazilian real-world setting
Michael Ruberson Ribeiro da Silva1,1, Jéssica Barreto Ribeiro Dos Santos1,1, Alessandra Maciel Almeida2,2
1Department of Social Pharmacy, Postgraduate Program in Medicines & Pharmaceutical Assistance, College of Pharmacy, Federal University of Minas Gerais, President Antônio Carlos Avenue, 6627, Campus Pampulha, Belo Horizonte, Minas Gerais 31270-901, Brazil.
Aim:
To evaluate the persistence of biological (TNF inhibitor [anti-TNF]) and synthetic (conventional synthetic disease-modifying antirheumatic drugs [csDMARDs]) antirheumatic agents for psoriatic arthritis and their associated factors.
Methods:
A historical cohort was developed. Persistence and associated factors were evaluated at 6 and 12 months.
Results:
A total of 161 patients were included. The anti-TNF treatment presented higher persistence as compared with csDMARDs at 6 (83.4 vs 50.8%; p < 0.05) and 12 months (66.4 vs 35.6%; p < 0.05). From anti-TNFs, adalimumab and etanercept presented similar persistence, along with leflunomide and methotrexate among the csDMARDs. The factors associated with non-persistence with regard to anti-TNF agents were female sex and use of infliximab.
Conclusion:
Anti-TNF agents are important therapeutic alternatives and present lower rates of discontinuation as compared with csDMARDs.
Related Concept Videos
Inhaled Medications
Setting Time of Cement
Documentation in Long-Term and Home Healthcare Setting
Long-Term Care Facilities
Specialized Care Centers and Settings-II
Rural health centers are specialized care facilities in remote locations with very few medical personnel. The primary care providers who run the centers are mostly Registered Nurse Practitioners. Here, emergency treatment is provided to critically ill or injured patients before they are transferred to the closest hospital. Fortunately, due to advancement in technology, many rural healthcare facilities and professionals have easy access to diagnostic and treatment...
PPE Use in Healthcare Settings I: Donning
PPE Use in Healthcare Settings II: Doffing

