Case of a Sister Mary Joseph's Nodule in a High Grade Serous Carcinoma

Sister Mary Joseph's nodule (SMJN) is a metastatic malignancy of the umbilicus usually indicative of advanced, metastatic disease. It is a rare occurrence, but it may be the first sign of abdominal cancer, most commonly an adenocarcinoma metastasis from a gastrointestinal or gynecologic primary malignancy. We present the case of an 82-year-old woman with an acute, 2 cm non-tender mass located at the umbilicus, diagnostic indication of an SMJN. Additional investigations included imaging via ultrasound and a pelvic magnetic resonance imaging (MRI) along with a biopsy and immunohistochemical staining in order to further characterize the mass. Our findings are discussed in the following case report.