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Merkel Cells: A Collective Review of Current Concepts
Jacob Abraham1, Sherin Mathew2
1Department of Orthodontics, Specialty Clinic, Dental and Orthodontic Center, Idukki, India.
Abstract:
Merkel cells (MCs) constitute a very unique population of postmitotic cells scattered along the dermo-epidermal junction. These cells that have synaptic contacts with somatosensory afferents are regarded to have a pivotal role in sensory discernment. Several concerns exist till date as to their origin, multiplication, and relevance in skin biology. The article, a collective review of literature extracted from PubMed search and dermatology books, provides novel insights into the physiology of MCs and their recent advances.
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