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Related Concept Videos

Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

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Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
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Heart Failure I: Introduction01:27

Heart Failure I: Introduction

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Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
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Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

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Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
872
Heart Failure Drugs: Diuretics01:22

Heart Failure Drugs: Diuretics

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Heart failure and kidney perfusion are interconnected in a complex way. Reduced renal perfusion and venous congestion are two significant factors that contribute to renal dysfunction in heart failure. The kidneys, primarily responsible for fluid balance in the body, are adversely affected due to compromised cardiac output and increased venous pressure. In response to reduced renal perfusion, the kidneys activate neurohumoral mechanisms to restore balance. However, these mechanisms can be...
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Heart Failure V: Medical Management01:30

Heart Failure V: Medical Management

272
Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
272
Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

314
Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
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Related Experiment Video

Updated: Jan 28, 2026

Author Spotlight: Investigating HR-Dependent Cardiac Function in Mouse Models Through a Novel Atrial-Pacing Approach
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[Telemedicine in heart failure].

F Köhler1, S Prescher2, K Köhler2

  • 1CharitéCentrum 11 für Herz‑, Kreislauf- und Gefäßmedizin, Medizinische Klinik und Poliklinik mit Schwerpunkt Kardiologie und Angiologie, Zentrum für kardiovaskuläre Telemedizin, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Deutschland. friedrich.koehler@charite.de.

Der Internist
|March 2, 2019
PubMed
Summary
This summary is machine-generated.

Telemedical co-management significantly reduces mortality and morbidity in heart failure patients, regardless of location. This approach is key to improving outpatient care and addressing regional disparities.

Keywords:
Call centersMonitoring, outpatient, remoteOutpatient careStandard careTelemedicine center

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Area of Science:

  • Cardiology
  • Health Services Research
  • Digital Health

Background:

  • Improved outpatient heart failure care is vital to reduce hospitalizations and mortality.
  • Regional and rural disparities in heart failure management present a significant challenge.
  • Telemedical care offers a promising supplement to traditional point-of-care medicine.

Purpose of the Study:

  • To present the technical and organizational foundations of telemedical methods in outpatient heart failure care.
  • To review current evidence on the efficacy of telemedical co-management in heart failure.
  • To highlight the scalability of telemedical concepts for nationwide implementation.

Main Methods:

  • Review of nine key randomized controlled trials on telemedicine in heart failure.
  • Detailed analysis of the TIM-HF2 study (2018) focusing on mortality and morbidity outcomes.
  • Examination of pre-stratified subgroup analyses, including urban and rural comparisons.

Main Results:

  • Telemedical co-management demonstrated superiority in reducing mortality and morbidity post-heart failure hospitalization.
  • No significant differences in primary endpoint efficacy were observed between urban and rural subgroups.
  • The TIM-HF2 study provides strong evidence for the effectiveness of telemedical interventions.

Conclusions:

  • Telemedical co-management is a highly effective strategy for improving outcomes in heart failure patients.
  • The approach is scalable and addresses geographical disparities in care.
  • Projects like Telemed5000 aim to leverage artificial intelligence for large-scale telemedical heart failure management.