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Published on: October 11, 2014
Meniscal allograft transplantation in the paediatric population: early referral is justified
S Middleton1, L Asplin1, C Stevenson1
1University Hospital Coventry and Warwickshire NHS Trust, Clifford Bridge Road, Coventry, CV2 2DX, UK.
Insights
Meniscal allograft transplantation (MAT) in children shows promising results, with no graft failures and improved knee function and pain reduction. This pediatric study supports MAT as a viable treatment for symptomatic meniscal-deficient knees.
Area of Science:
- Orthopedics
- Pediatric Surgery
- Sports Medicine
Background:
- Meniscal allograft transplantation (MAT) is effective in adults but rarely studied in children.
- Limited evidence exists on the long-term outcomes and survivorship of pediatric MAT.
Purpose of the Study:
- To evaluate the clinical outcomes and survivorship of meniscal allograft transplantation (MAT) in a pediatric population.
- To assess the efficacy of MAT in improving function and reducing pain in children with meniscal deficiency.
Main Methods:
- A prospective database analysis of 23 pediatric patients (aged 8-18) who underwent MAT.
- Median follow-up of 3.8 years, with assessment of graft survival and validated knee outcome scores (KOOS, Lysholm, Tegner, IKDC).
Main Results:
- No cases of graft failure were reported in the study cohort.
- Significant improvements were observed in all KOOS subscales, Lysholm, Tegner, and IKDC scores.
- Four patients required secondary procedures; no infections occurred.
Conclusions:
- Meniscal allograft transplantation (MAT) is a viable and effective treatment for symptomatic pediatric patients with meniscal deficiency.
- MAT can lead to significant improvements in knee function and pain reduction in the pediatric population.
- Early referral for MAT should be considered for children experiencing persistent symptoms after meniscectomy.
Purpose:
The need for meniscal allograft transplantation (MAT) in children is rare, and as a result, there is a paucity of evidence detailing survivorship and clinical outcome. MAT has been shown to significantly reduce pain and improve function in the adult population. The aim of this study was to document the outcomes of a single surgeon case series of MAT in the paediatric population.
Methods:
Analysis of a prospective meniscal allograft transplantation (MAT) group database of 280 patients was performed. Twenty-three patients met the inclusion criteria-undergoing MAT aged 18 years or younger.
Results:
Fourteen were female and nine were male with median age of 17 (range 8-18). Thirteen (57%) were right knee and nineteen (83%) were lateral. Additional procedures included high tibial osteotomy, anterior cruciate ligament reconstruction, and microfracture procedures. The median follow-up was 3.8 years (range of 0.2 to 7.8 years). There have been no cases of graft failure. All patients demonstrated improvement in all the modalities of the KOOS outcome scores. At 5 years, the Lysholm score had improved from 57.9 to 87.6 (SD 12.1), Tegner activity score had improved from 2 to 5 (range 4-7) and IKDC score had improved from 40.6 to 78.6 (SD 15.8). Four patients required secondary surgical intervention. No patients developed a superficial or deep infection.
Conclusion:
Meniscal allograft transplantation in children is founded on the successful results of MAT in the adult population. We have demonstrated in this series that MAT can improve function and reduce pain in the paediatric population, and is, therefore, a viable treatment option for the management of the symptomatic paediatric meniscal-deficient knee. Early referral should be considered in the patients with post-meniscectomy syndrome, pain on weight bearing with a history of previous menisectomy.
Level Of Evidence:
IV.
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