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Updated: Jan 28, 2026

FISH for Pre-implantation Genetic Diagnosis
Published on: February 23, 2011
A diagnosis reconsidered: the symptomatic gallbladder remnant
Julie G Grossman1, William R Johnston1, Kathryn J Fowler2
1Department of Surgery, Barnes-Jewish Hospital and the Alvin J. Siteman Cancer Center at Washington University School of Medicine, 660 South Euclid Avenue, Box 8109, St. Louis, MO, 63110, USA.
Symptomatic gallbladder remnant after surgery is rare but treatable. Completion cholecystectomy offers definitive relief for most patients experiencing recurrent biliary symptoms post-gallbladder removal.
Area of Science:
- Gastroenterology
- Surgical Innovation
- Diagnostic Imaging
Background:
- Gallbladder remnant disease presents a diagnostic challenge post-cholecystectomy.
- Symptomatic gallbladder remnants are infrequently characterized.
Purpose of the Study:
- To characterize the presentation, diagnosis, and treatment of symptomatic gallbladder remnants.
- To evaluate the effectiveness of various diagnostic and therapeutic modalities.
Main Methods:
- Retrospective review of 31 patients with symptomatic gallbladder remnants (2002-2016).
- Analysis of presenting symptoms, diagnostic imaging (ERCP, MRCP), and treatment outcomes.
- Comparison of surgical versus non-operative management.
Main Results:
- Right upper quadrant pain and nausea were common symptoms.
- Endoscopic retrograde cholangiopancreatography (ERCP) and magnetic resonance cholangiopancreatography (MRCP) showed high sensitivity (85-90%).
- Completion cholecystectomy was definitive for 76.2% of patients; non-operative management had higher recurrence rates.
Conclusions:
- Symptomatic gallbladder remnant should be considered in post-cholecystectomy patients with recurrent biliary pain.
- Completion cholecystectomy, though challenging, is an effective treatment.
- ERCP and MRCP are valuable diagnostic tools for gallbladder remnants.
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