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Engineering Antiviral Agents via Surface Plasmon Resonance

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Localized surface plasmon resonance biosensor: an improved technique for SERS response intensification.

Md Saiful Islam, Jakeya Sultana, Rifat Ahmmed Aoni

|March 2, 2019

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Researchers developed a novel microstructured polymer sensor combining wave-guiding and plasmonic resonance. This localized surface plasmon resonance system achieves record sensitivity for advanced biosensing applications.

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Area of Science:

Nanotechnology
Materials Science
Optics

Background:

Advancing technology enables novel sensing systems for practical biosensing.
Localized surface plasmon resonance (LSPR) is a key technology for biosensing.

Purpose of the Study:

To demonstrate a novel LSPR system combining wave-guiding and plasmonic resonance.
To develop a low-cost, practical biosensing platform using a single microstructured polymeric structure.

Main Methods:

Utilized a microstructured polymeric structure for combined wave-guiding and plasmonic resonance.
Employed finite element method (FEM) simulations for sensor characterization.

Main Results:

Achieved a record wavelength sensitivity (WS) of 111000 nm/RIU.
Demonstrated high amplitude sensitivity (AS) of 2050 RIU^-1.
Obtained high sensor resolution (9×10^-7 RIU) and limit of detection (8.12×10^-12 RIU²/nm).

Conclusions:

The developed sensor shows potential for biomolecular and chemical analyte detection.
The system is suitable for applications requiring detection within a refractive index range of 1.33-1.43.
The sensor operates effectively in the visible to mid-infrared spectrum.