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Comparative and Functional Algal Genomics.

Crysten E Blaby-Haas1, Sabeeha S Merchant2,3

  • 1Biology Department, Brookhaven National Laboratory, Upton, New York 11973, USA;

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|March 2, 2019
PubMed
Summary
This summary is machine-generated.

Over 100 algal genome sequences are available, revealing vast unknown protein functions. This resource aids understanding of diverse photosynthetic eukaryotes and guides future functional genomics research.

Keywords:
chloroplastcytochromeendosymbiosisflavodoxinsequence similarity network

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Area of Science:

  • * Eukaryotic genomics
  • * Photosynthetic eukaryotes
  • * Marine biology

Background:

  • * Algae represent a highly diverse, complex, and understudied group of photosynthetic eukaryotes.
  • * Over 100 whole-genome sequences from algae are now available or forthcoming.
  • * Genomic data is crucial for understanding algal diversity and function.

Purpose of the Study:

  • * To review publicly available algal genome sequences and their protein inventories.
  • * To assess the quality of these genomic resources.
  • * To summarize the current understanding and prediction status of protein functions in algae.

Main Methods:

  • * Compilation and analysis of publicly available algal genome sequences.
  • * Inventory and quality assessment of encoded proteins.
  • * Review of existing literature on algal protein function annotation and prediction.

Main Results:

  • * A rapidly increasing number of algal whole-genome sequences are accessible.
  • * Over half of the proteins encoded by algal genomes have unknown functions.
  • * Significant potential for discovering novel functional capabilities within algal genomes.

Conclusions:

  • * Publicly available algal genomes are invaluable resources for biological research.
  • * The vast number of proteins with unknown functions presents a major frontier for discovery.
  • * Phylogenomics and functional genomics are key tools for advancing our understanding of algal biology.