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A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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(2S)-N-2-methoxy-2-phenylethyl-6,7-benzomorphan compound (2S-LP2): Discovery of a biased mu/delta opioid receptor

Lorella Pasquinucci1, Rita Turnaturi1, Girolamo Calò2

  • 1Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125 Catania, Italy.

European Journal of Medicinal Chemistry
|March 2, 2019
PubMed

Keywords:
Asymmetric synthesisBRETG-proteinMultitargetPainRadioligand competition bindingTail flick testβ-arrestin

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