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Related Experiment Video

Updated: Jan 28, 2026

RNAi-mediated Control of Aflatoxins in Peanut: Method to Analyze Mycotoxin Production and Transgene Expression in the Peanut/Aspergillus Pathosystem

RNAi-mediated Control of Aflatoxins in Peanut: Method to Analyze Mycotoxin Production and Transgene Expression in the Peanut/Aspergillus Pathosystem

Published on: December 21, 2015

Aflatoxin M in Perspective ¹.

Leonard Stoloff¹

¹Division of Food Technology, Food and Drug Administration, Washington, DC 20204.

Journal of Food Protection

|March 3, 2019

Summary

This summary is machine-generated.

Aflatoxin M1 contaminates milk from cows consuming aflatoxin B1-contaminated feed. Despite regulatory efforts, its presence necessitates guidelines for milk products to ensure consumer safety.

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Inhibition of Aspergillus flavus Growth and Aflatoxin Production in Transgenic Maize Expressing the α-amylase Inhibitor from Lablab purpureus L.

Inhibition of Aspergillus flavus Growth and Aflatoxin Production in Transgenic Maize Expressing the α-amylase Inhibitor from Lablab purpureus L.

Published on: February 15, 2019

Area of Science:

Food Science
Toxicology
Animal Nutrition

Background:

Aflatoxin M1 is a metabolite of aflatoxin B1, a common contaminant in animal feed.
The presence of aflatoxin M1 in milk poses a potential risk to human health.

Purpose of the Study:

To investigate the relationship between aflatoxin B1 exposure in dairy cows and aflatoxin M1 levels in milk.
To assess the prevalence of aflatoxin M1 in commercial milk supplies.
To inform regulatory guidelines for aflatoxin M1 in milk products.

Main Methods:

Controlled studies estimating aflatoxin M1 levels in milk based on aflatoxin B1 intake.
Analysis of survey data on aflatoxin M1 in commercial milk.
Review of regulatory actions and guidelines by the Food and Drug Administration.

Main Results:

Aflatoxin B1 in dairy feed is sufficiently high to cause measurable aflatoxin M1 (> 0.1 ng/ml) in milk.
Experimental estimates are corroborated by survey data, confirming widespread occurrence.
Regulatory control of feed has not prevented aflatoxin M1 occurrence in milk.

Conclusions:

Aflatoxin M1 is a common contaminant in U.S. milk supplies due to aflatoxin B1 in feed.
An administrative guideline of 0.5 ppb for aflatoxin M1 in milk has been established.
Further consideration is being given to guidelines for milk-derived products.