Pediatric trauma-related coagulopathy: Balanced resuscitation, goal-directed therapy and viscoelastic assays

Natalie A Drucker1, S Keisin Wang1, Christopher Newton2

  • 1Department of Surgery, Section of Pediatric Surgery, Riley Hospital for Children, Indianapolis, IN, United States.

Insights

Research on pediatric trauma-induced coagulopathy is limited, necessitating further investigation into age-related hemostasis and balanced resuscitation strategies for improved hemorrhage control.

Area of Science:

  • Pediatric critical care medicine
  • Trauma surgery
  • Hematology

Background:

  • Trauma-induced coagulopathy understanding has advanced adult damage-control resuscitation.
  • Pediatric trauma research on coagulopathy and resuscitation remains sparse.
  • There is a significant need for more evidence in pediatric trauma care.

Purpose of the Study:

  • To review current pediatric data on trauma-induced coagulopathy.
  • To examine applicable adult data for pediatric relevance.
  • To identify future research areas impacting pediatric trauma care.

Main Methods:

  • Literature review of pediatric trauma-induced coagulopathy.
  • Analysis of adult data applicable to pediatric populations.
  • Identification of emerging research topics in pediatric hemostasis.

Main Results:

  • Limited evidence exists for pediatric trauma-induced coagulopathy.
  • Age-related hemostatic differences require further study.
  • Advances in coagulation assays and medications like tranexamic acid show promise.

Conclusions:

  • Pediatric trauma care requires tailored approaches to coagulopathy.
  • Further research is crucial for optimizing resuscitation strategies.
  • Future investigations will focus on age-specific hemostasis and hemorrhage control.

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