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Functional status in a geriatric oncology setting: A review
Anne-Laure Couderc1, Rabia Boulahssass2, Emilie Nouguerède3
1Division of Internal Medicine, Geriatry and Therapeutic, Sainte Marguerite Hospital, AP-HM, Marseille, France; Coordination Unit for Geriatric Oncology (UCOG), PACA West, France.
Journal of Geriatric Oncology
|March 3, 2019
Summary
Functional Status (FS) assessment in older cancer patients predicts outcomes like survival and toxicity. Tools like Katz ADL and Lawton IADL are common, but more research is needed to refine prognostic value.
Area of Science:
- Geriatric Oncology
- Cancer Research
- Clinical Assessment
Background:
- Comprehensive Geriatric Assessment (CGA) identifies frailties in older cancer patients to guide treatment.
- Functional Status (FS) is a key component of CGA, utilizing Activities of Daily Living (ADL) and Instrumental Activities of Daily Living (IADL) assessments.
Purpose of the Study:
- To review commonly used ADL and IADL tools in geriatric oncology.
- To evaluate the predictive value of FS on overall survival, toxicity, treatment decisions, and complications.
Main Methods:
- Systematic literature search of MEDLINE database (2010-2017).
- Inclusion of 40 studies from 4061 identified articles.
- Focus on ADL and IADL assessment tools in older cancer patients.
Main Results:
- Katz ADL (KL-ADL) and Lawton IADL were the most frequently used scales.
- FS demonstrated predictive value for overall survival (11/24 studies).
- FS showed predictive value for postoperative complications (4/6 studies), treatment decisions (2/3 studies), and treatment feasibility (2/5 studies).
Conclusions:
- Functional Status holds prognostic value in geriatric oncology, despite methodological variations.
- Further research is essential to precisely define the prognostic impact of FS on survival, toxicity, treatment, and complications in this population.
Keywords:
CancerChemotoxicityFunctional statusOlder adultsOverall survivalPostoperative complicationsTreatment decisionTreatment feasibilityMore Related Videos
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