Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

5.6K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
5.6K
Pulmonary Function Tests01:25

Pulmonary Function Tests

797
Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
797
The Thyroid Gland01:23

The Thyroid Gland

7.6K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
7.6K
Serum Studies: Renal Function Tests01:24

Serum Studies: Renal Function Tests

429
Renal function tests are crucial for assessing kidney health, monitoring disease progression, and evaluating the kidneys' efficiency in waste elimination, fluid balance, and electrolyte regulation. These tests offer critical insights into kidney function, even though routine measurements may appear normal until there is a significant decline in the glomerular filtration rate or GFR. Typically, signs of kidney impairment only become evident when the GFR falls to about 50% of its normal level.
429
Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

7.8K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
7.8K
Bioavailability Study Design: Healthy Subjects Versus Patients01:15

Bioavailability Study Design: Healthy Subjects Versus Patients

147
Bioavailability studies are essential for evaluating a drug's therapeutic efficacy and understanding its absorption patterns under various physiological conditions. Conducting such studies on target patient populations provides more relevant data by simulating real-world disease states. However, practical challenges often necessitate the use of young, healthy adult volunteers as study subjects.Patients may exhibit altered drug absorption patterns due to the effects of the disease itself,...
147

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prioritisation processes for programme implementation and evaluation in public health: A scoping review.

Frontiers in public health·2023
Same author

A Multidisciplinary Investigation into the Talent Development Processes at an English Football Academy: A Machine Learning Approach.

Sports (Basel, Switzerland)·2022
Same author

Economic impact of a rapid, on-demand ADAMTS-13 activity assay for the diagnosis of thrombotic thrombocytopenic purpura.

Research and practice in thrombosis and haemostasis·2022
Same author

An alliance with public health in pursuit of COVID-19 evidence.

Occupational medicine (Oxford, England)·2020
Same author

Pedometers can help people get more active as part of an exercise programme.

BMJ (Clinical research ed.)·2020
Same author

Computerised speech and language therapy can help people with aphasia find words following a stroke.

BMJ (Clinical research ed.)·2020
Same journal

Peptides: FDA appointed advisory committee criticised for conflicts of interest.

BMJ (Clinical research ed.)·2026
Same journal

Hantavirus outbreak linked to cruise ship is over, say officials.

BMJ (Clinical research ed.)·2026
Same journal

BMA recommends that 16 and 17 year olds get access to cross sex hormones.

BMJ (Clinical research ed.)·2026
Same journal

Andy Burnham could apply lessons from Manchester to create a healthier Britain with a stronger economy.

BMJ (Clinical research ed.)·2026
Same journal

Uganda confirms Marburg case as Ebola outbreak continues.

BMJ (Clinical research ed.)·2026
Same journal

Australia increases penalties for social media companies to enforce under 16s ban.

BMJ (Clinical research ed.)·2026
See all related articles

Related Experiment Video

Updated: Jan 28, 2026

Author Spotlight: Accurately Assessing Thyroid Hormone-Driven Motor Alterations in Mouse
04:05

Author Spotlight: Accurately Assessing Thyroid Hormone-Driven Motor Alterations in Mouse

Published on: October 6, 2023

761

Repeat thyroid function tests for healthy older people are not needed.

Rob Cook1, Duncan Fortescue-Webb2, Rachel Taft3

  • 1Bazian, Economist Intelligence Unit healthcare, London, UK rob.cook@bazian.com.

BMJ (Clinical Research Ed.)
|March 3, 2019
PubMed
Summary
This summary is machine-generated.

Repeat thyroid function tests are unnecessary for healthy older adults. This study found thyroid function remains stable in this population, suggesting routine retesting is not clinically beneficial.

More Related Videos

Author Spotlight: Developing Low-Tech Balance Assessment Methods for Broad-Spectrum Healthcare Applications
06:28

Author Spotlight: Developing Low-Tech Balance Assessment Methods for Broad-Spectrum Healthcare Applications

Published on: September 1, 2023

6.2K
Effects of Surgical Masks on Cardiopulmonary Function in Healthy Subjects
06:57

Effects of Surgical Masks on Cardiopulmonary Function in Healthy Subjects

Published on: February 12, 2021

3.6K

Related Experiment Videos

Last Updated: Jan 28, 2026

Author Spotlight: Accurately Assessing Thyroid Hormone-Driven Motor Alterations in Mouse
04:05

Author Spotlight: Accurately Assessing Thyroid Hormone-Driven Motor Alterations in Mouse

Published on: October 6, 2023

761
Author Spotlight: Developing Low-Tech Balance Assessment Methods for Broad-Spectrum Healthcare Applications
06:28

Author Spotlight: Developing Low-Tech Balance Assessment Methods for Broad-Spectrum Healthcare Applications

Published on: September 1, 2023

6.2K
Effects of Surgical Masks on Cardiopulmonary Function in Healthy Subjects
06:57

Effects of Surgical Masks on Cardiopulmonary Function in Healthy Subjects

Published on: February 12, 2021

3.6K

Area of Science:

  • Geriatric Medicine
  • Endocrinology
  • Primary Care Research

Background:

  • Thyroid dysfunction is common in older adults.
  • Current guidelines often recommend routine thyroid function monitoring in the elderly.
  • The stability of thyroid function in healthy older individuals requires further investigation.

Purpose of the Study:

  • To assess the stability of thyroid function over time in a cohort of healthy older adults.
  • To determine if repeat thyroid function testing is necessary for this demographic.

Main Methods:

  • Longitudinal study design.
  • Analysis of thyroid function test results (Thyroid Stimulating Hormone - TSH) from a cohort of elderly participants.
  • Inclusion criteria focused on individuals without diagnosed thyroid disease or recent thyroid-related interventions.

Main Results:

  • Thyroid function, specifically TSH levels, demonstrated significant stability over the study period in healthy older adults.
  • No clinically significant changes in thyroid function were observed that would necessitate routine retesting.
  • The findings support the hypothesis that thyroid function is generally stable in this population.

Conclusions:

  • Routine repeat thyroid function tests are not indicated for healthy older adults.
  • Discontinuation of regular thyroid monitoring in this group may be considered, potentially reducing healthcare costs and patient burden.