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Discussion on Brain Structure and Function in Schizophrenia by Multimodal Magnetic Resonance Imaging
Xiaohui Zhi1, Lin Cai2, Na Guo3
1Department of Medical Imaging, The Fourth Hospital of Harbin Medical University, No.37 Yiyuan Road, Harbin City, 150001, Heilongjiang Province, China.
Abstract:
In order to explore the relationship between hippocampal structure changes and performance symptoms as well as cognitive function in adolescent schizophrenia, taking the brain response signals of psychiatric patients as the research object, the relationship between hippocampal volume drawn by schizophrenia and language memory of negative symptoms is explored based on morphological analysis method. It is found that the left hippocampal volume of schizophrenic patients is abnormal when the whole brain volume is returned, which is significantly lower than that of normal people. It is also found that the left hippocampus volume of schizophrenic patients is a mediator between negative symptoms and speech memory. The results show that the left hippocampus of schizophrenic patients plays an important role in the pathogenesis of schizophrenia.
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