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Accelerators in concrete serve as admixtures to speed up the hardening process, enabling the concrete to achieve early strength faster. Although accelerators do not necessarily impact the time it takes concrete to set, they reduce this time in practice. A common accelerator is calcium chloride, which is particularly useful for hastening early strength development in cold weather or for rapid repair jobs that require quick heat generation after mixing.
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The importance of understanding acceleration spans our day-to-day experiences, as well as the vast reaches of outer space and the tiny world of subatomic physics. In everyday conversation, to accelerate means to speed up. For instance, we are familiar with the acceleration of our car; the harder we apply our foot to the gas pedal, the faster we accelerate. The greater the acceleration, the greater the change in velocity over a given time. Acceleration is widely seen in experimental physics. In...
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Radiation Planning Assistant - A Streamlined, Fully Automated Radiotherapy Treatment Planning System
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Auto-planning for VMAT accelerated partial breast irradiation.

Livia Marrazzo1, Icro Meattini2, Chiara Arilli1

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Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology
|March 4, 2019
PubMed
Summary
This summary is machine-generated.

Automated planning for volumetric modulated arc therapy accelerated partial breast irradiation (VMAT APBI) significantly improved target coverage and reduced planning time compared to manual methods. The auto-planning module proved superior in quality and efficiency for APBI treatment plans.

Keywords:
Automatic planningBreast cancerPartial breast irradiationVMAT

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Area of Science:

  • Radiation Oncology
  • Medical Physics
  • Cancer Treatment Planning

Background:

  • Accelerated partial breast irradiation (APBI) is a widely used technique for early-stage breast cancer.
  • Manual treatment planning systems (TPS) can be time-consuming and may yield suboptimal plan quality.
  • Automated planning offers a potential solution to improve efficiency and consistency in radiation therapy.

Purpose of the Study:

  • To evaluate the dosimetric quality and efficiency of an automated planning (AP) module for VMAT APBI.
  • To compare APBI plans generated by the AP module against manually planned treatments.

Main Methods:

  • Twenty patients previously treated with manual APBI plans (manM) were re-planned using a different TPS with manual (manP) and automatic (AP) planning.
  • Plans were assessed for dosimetric parameters, modulation, monitor units, treatment time, and physician qualitative scoring.
  • Dosimetric verification included gamma (γ) passing rate and point dose measurements; statistical analysis used Wilcoxon's signed-rank test.

Main Results:

  • AP plans demonstrated statistically significant improvements in planning target volume (PTV) coverage and homogeneity compared to both manM and manP plans.
  • No significant differences were observed in organs at risk doses or γ passing rates between the planning methods.
  • AP planning drastically reduced planning time (from ~60 minutes to ~10 minutes) and was qualitatively rated as superior by physicians.

Conclusions:

  • The automated planning module for VMAT APBI is at least equivalent and generally superior to manual planning in terms of plan quality.
  • Auto-planning significantly enhances efficiency, reducing treatment planning time substantially.
  • This technology holds promise for improving the delivery of APBI.